IgG Subclasses in Selective IgA Deficiency Importance of IgG2-IgA Deficiency

• Published in: The New England journal of medicine Vol. 304; no. 24; pp. 1476 - 1477
• Main Authors: Oxelius, Vivi-Anne, Laurell, Anna-Brita, Lindquist, Bertil, Golebiowska, Henryka, Axelsson, Uno, Björkander, Janne, Hanson, Lars Å
• Format: Journal Article
• Language: English
• Published: United States Massachusetts Medical Society 11.06.1981
• Subjects: Adolescent; Adult; Ataxia; Autoimmune diseases; Case reports; Child; Child, Preschool; Disease; Dysgammaglobulinemia - immunology; Humans; IgA Deficiency; IgG Deficiency; Immunoglobulin A; Immunoglobulin G; Immunoglobulins; Infant; Infections

A SELECTIVE deficiency in IgA appears in about one in 700 persons. 1 Many of these persons are healthy, 2 but there is an increased frequency of infections, autoimmune disorders, atopy, and malabsorption syndromes in such subjects. 3 In an attempt to explain why some IgA-deficient patients have illn...