Toxicokinetic modeling of [ 14C]pentachlorophenol in the rainbow trout ( Salmo gairdneri)

• Published in: Aquatic toxicology Vol. 9; no. 1; pp. 59 - 80
• Main Authors: McKim, James M., Schmieder, Patricia K., Erickson, Russell J.
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 1986; Elsevier Science
• Subjects: Biological and medical sciences; Environmental pollutants toxicology; Fish; Medical sciences; Pentachlorophenol; Toxicokinetics; Toxicology; Water; Toxicokinetics; Fish; Pentachlorophenol; Pollutant; Vertebrata; Excretion; Pisces; Animal; Fresh water; Salmo gairdneri; Metabolism; Labelled compound

An in vivo trout model was used to monitor the major routes and rates of pentachlorophenol uptake and elimination. Rainbow trout exposed to a mean sublethal water concentration (1.0 μg/l) of [ 14C]pentachlorophenol (PCP), a moderately lipophilic, relatively non-persistent environmental contaminant a...