Increased sodium–proton antiporter activity in patients with obstructive sleep apnoea

• Published in: Journal of sleep research Vol. 9; no. 3; pp. 285 - 291
• Main Authors: Tepel, Martin, Sanner, Bernd M., Van Der Giet, Marcus, Zidek, Walter
• Format: Journal Article
• Language: English
• Published: Oxford UK Blackwell Science Ltd 01.09.2000
• Subjects: Aged; Antiporters - blood; Cytosol - metabolism; Electromyography; Female; fluorescent dye; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Ion Transport - physiology; lymphocytes; Lymphocytes - metabolism; Male; Middle Aged; obstructive sleep apnoea; Polysomnography; Protons; Sleep - physiology; Sleep Apnea, Obstructive - blood; Sodium Chloride - blood; sodium–proton antiporter

Cytosolic pH (pHi) and the activity of the sodium–proton antiporter (Na+/H+ antiporter) were measured in lymphocytes from 22 patients with obstructive sleep apnoea and from 24 age‐matched healthy subjects (Controls). The cellular Na+/H+ antiporter was measured spectrophotometrically using a pH‐sensi...