A functional polymorphism of the OXTR gene is associated with autistic traits in Caucasian and Asian populations

• Published in: American journal of medical genetics. Part B, Neuropsychiatric genetics Vol. 174; no. 8; pp. 808 - 816
• Main Authors: Montag, Christian, Sindermann, Cornelia, Melchers, Martin, Jung, Sonja, Luo, Ruixue, Becker, Benjamin, Xie, Jiang, Xu, Wenming, Guastella, Adam J., Kendrick, Keith M.
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.12.2017
• Subjects: Adult; Alleles; Asian Continental Ancestry Group - genetics; Autism; autism‐spectrum quotient; Autistic Disorder - epidemiology; Autistic Disorder - genetics; Case-Control Studies; European Continental Ancestry Group - genetics; Female; Gene polymorphism; Genetics; Genotype; Genotyping; Humans; Linkage Disequilibrium; Male; Oxytocin; oxytocin receptor gene; Polymorphism, Single Nucleotide; Quantitative Trait, Heritable; Receptors, Oxytocin - genetics; rs2268498; Single-nucleotide polymorphism; White people; Young Adult; oxytocin; genetics; oxytocin receptor gene; rs2268498; autism; autism-spectrum quotient

There is increasing evidence for associations between polymorphisms of the oxytocin receptor (OXTR) gene and autism spectrum disorder, but to date no study has established links with autistic traits in healthy subjects and potential cultural differences. The present research firstly investigated ass...