Clinical, immunophenotypic, and cytogenetic characteristics of high‐grade myelodysplastic syndromes with CD41‐positive progenitor cells

• Published in: Cytometry. Part B, Clinical cytometry Vol. 104; no. 1; pp. 98 - 107
• Main Authors: Ogata, Kiyoyuki, Sei, Kazuma, Kawahara, Naoya, Ogata, Mika, Yamamoto, Yumi
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.01.2023; Wiley Subscription Services, Inc
• Subjects: Acute myeloid leukemia; Antigens; Bone marrow; Bone Marrow - pathology; CD13 antigen; CD41; CD45 antigen; Cytogenetics; Disorders; Flow Cytometry; Humans; immunophenotypes; Karyotypes; Karyotyping; Leukemia; Lymphocytes; Medical prognosis; Monocytes; Myelodysplastic syndrome; myelodysplastic syndromes; Myelodysplastic Syndromes - diagnosis; Myelodysplastic Syndromes - genetics; Myelodysplastic Syndromes - pathology; Osteoprogenitor cells; Progenitor cells; Stem Cells - pathology; CD41; cytogenetics; myelodysplastic syndromes; immunophenotypes
• ISSN: 1552-4949; 1552-4957; 1552-4957
• DOI: 10.1002/cyto.b.22052

Background: Patients with myelodysplastic syndromes (MDS) with progenitors expressing CD41 (CD41+ MDS) showed a poor prognosis in a previous study but their detailed characteristics remain unclear. Methods: One hundred thirty‐seven subjects at our institution were diagnosed with excess blasts (EB)‐1...