Relationship of Muscle Mass Determined by DEXA with Spirometric Results in Healthy Individuals

• Published in: Archivos de bronconeumología (English ed.) Vol. 53; no. 7; pp. 375 - 380
• Main Authors: Martín Holguera, Rafael, Turrión Nieves, Ana Isabel, Rodríguez Torres, Rosa, Alonso, María Concepción
• Format: Journal Article
• Language: English
• Published: Spain Elsevier España, S.L.U 01.07.2017
• Subjects: Absorciometría dual fotónica de rayos X; Absorptiometry, Photon; Adolescent; Adult; Aged; Body Composition; Body Mass Index; Dual energy X-ray absorptiometry; Espirometría; Fat-free soft tissue mass; Female; Humans; Internal Medicine; Lean body mass; Male; Middle Aged; Muscle, Skeletal - anatomy & histology; Organ Size; Principal Component Analysis; Pulmonary/Respiratory; Reference Values; Spirometry; Tejido blando no graso; Tejido magro; Thinness; Young Adult; Dual energy X-ray absorptiometry; Spirometry; Lean body mass; Tejido blando no graso; Absorciometría dual fotónica de rayos X; Tejido magro; Espirometría; Fat-free soft tissue mass
• ISSN: 1579-2129; 1579-2129
• DOI: 10.1016/j.arbr.2017.05.006

Abstract Introduction Muscle mass maybe a determining factor in the variability of spirometry results in individuals of the same sex and age who have similar anthropometric characteristics. The aim of this study was to determine the association between spirometric results from healthy individuals and their muscle mass assessed by dual energy X-ray absorptiometry (DEXA). Methods A sample of 161 women and 144 men, all healthy non-smokers, was studied. Ages ranged from18 to77 years. For each subject, spirometry results and total and regional lean mass values obtained by full body DEXA were recorded. A descriptive analysis of the variables and a regression analysis were performed to study the relationship between spirometric variables and lean body mass, correcting for age and body mass index (BMI). Results In both sexes all muscle mass variables correlated positively and significantly with spirometric variables, and to a greater extent in men. After partial adjustment of correlations by age and BMI, the factor which best explains the spirometric variables is the total lean body mass in men, and trunk lean body mass in women. Conclusions In men, muscle mass in the lower extremities is most closely associated with spirometric results. In women, it is the muscle mass of the trunk. In both sexes muscle mass mainly affects FEV1.