Suppressive effect of resveratrol, catechin and their conformationally constrained analogs on neutrophil extracellular trap formation by HL-60-derived neutrophils

• Published in: Journal of Clinical Biochemistry and Nutrition Vol. 75; no. 1; pp. 17 - 23
• Main Authors: Ohinata, Hitomi, Phimarn, Wiraphol, Mizuno, Mirei, Obama, Takashi, Fukuhara, Kiyoshi, Makiyama, Tomohiko, Watanabe, Yuichi, Itabe, Hiroyuki
• Format: Journal Article
• Language: English
• Published: Japan SOCIETY FOR FREE RADICAL RESEARCH JAPAN 01.01.2024; Japan Science and Technology Agency
• Subjects: Acetic acid; Analogs; Aromatic compounds; Arteriosclerosis; Atherosclerosis; Calcium compounds; Calcium ionophores; Catechin; Conformation; Constraints; Deoxyribonucleic acid; DNA; HL-60; Hydrophobicity; Lecithin; Leukocytes (neutrophilic); neutrophil extracellular trap; Neutrophils; Peroxidase; Phosphatidylcholine; Phospholipids; planar analog; Resveratrol; catechin; HL-60; resveratrol; planar analog; neutrophil extracellular trap

Neutrophil extracellular trap (NET) formation is a unique self-defense mechanism of neutrophils; however, it is also involved in many diseases, including atherosclerosis. Resveratrol and catechin are antioxidants with anti-atherosclerotic properties. Here, we examined the effects of resveratrol, cat...