Design, synthesis and biological evaluation of soluble 2,5-diketopiperazines derivatives as potential antifouling agents

• Published in: RSC advances Vol. 5; no. 63; pp. 51020 - 51026
• Main Authors: Liao, Shengrong, Xu, Ying, Tang, Yong, Wang, Junfeng, Zhou, Xuefeng, Xu, Liang, Liu, Yonghong
• Format: Journal Article
• Language: English
• Published: 01.01.2015
• Subjects: active ingredients; Antifouling; antifouling activities; antifouling agents; aquatic organisms; Attachment; Balanus amphitrite; biological assessment; Cheilostomata; Derivatives; fouling; larvae; Libraries; Marine; median effective concentration; Organisms; Synthesis; Toxicity

A small library of soluble 2,5-diketopiperazine derivatives were designed, synthesized and evaluated as antifouling agents against two species of marine organisms: Balanus amphitrite and Bugula neritina by larval attachment assay. The results showed that different derivatives had different antifouli...