Laser welding of pre-functionalized glass substrates: a fabrication and chemical stability study

Low-temperature bonding of glass substrates is of great interest in the field of microfluidic-based biosensing, and we study how laser welding could be used for this. This technology allows for the modification of glass channels with temperature-sensitive materials prior to bonding. We study the eff...

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Bibliographic Details
Published inJournal of micromechanics and microengineering Vol. 28; no. 1; pp. 15002 - 15007
Main Authors Carvalho, R R, Reuvekamp, S, Zuilhof, H, Blom, M T, Vrouwe, E X
Format Journal Article
LanguageEnglish
Published IOP Publishing 01.01.2018
Subjects
glass
laser welding
low temperature bonding
microfluidics
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Summary:Low-temperature bonding of glass substrates is of great interest in the field of microfluidic-based biosensing, and we study how laser welding could be used for this. This technology allows for the modification of glass channels with temperature-sensitive materials prior to bonding. We study the effects of the welding process by investigation of the thermal degradation of a biotin monolayer and whether it retains the ability to conjugate with fluorescently-labelled streptavidin.
Bibliography:JMM-103035.R2
ISSN:0960-1317
1361-6439
DOI:10.1088/1361-6439/aa9962