Adaptation of corticosterone--but not beta-endorphin--secretion to repeated blood sampling in rats
Effects of short-term repeated blood sampling on the secretion of corticosterone (CORT) and beta-endorphin (beta-END) were evaluated in male Wistar rats. Blood was drawn from the tail vein of conscious rats four times within 2 h both at the peak and trough period of the diurnal corticosterone secret...
Saved in:
Published in | Laboratory animals (London) Vol. 33; no. 2; pp. 185 - 191 |
---|---|
Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
London, England
SAGE Publications
01.04.1999
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Effects of short-term repeated blood sampling on the secretion of corticosterone (CORT) and beta-endorphin (beta-END) were evaluated in male Wistar rats. Blood was drawn from the tail vein of conscious rats four times within 2 h both at the peak and trough period of the diurnal corticosterone secretion cycle. All rats were well accustomed to the procedure. The main findings were: (1) At both sampling intervals, CORT increased significantly in response to the first sampling and declined to baseline values in successive sample. (2) beta-END also increased significantly in response to the first sampling but remained elevated in successive samples. (3) Intensities of initial CORT and beta-END responses correlated positively with each other and with the baseline beta-END values. Feedback inhibition of CORT secretion with sustained elevation of beta-END titres suggests a moderate stress intensity of the repeated blood sampling procedures. In general, due to lack of short-term feedback inhibition, beta-END seems to reflect the effects of repeated administration of moderate intense stressors more closely than CORT. |
---|---|
AbstractList | Effects of short-term repeated blood sampling on the secretion of corticosterone (CORT) and beta-endorphin (beta-END) were evaluated in male Wistar rats. Blood was drawn from the tail vein of conscious rats four times within 2 h both at the peak and trough period of the diurnal corticosterone secretion cycle. All rats were well accustomed to the procedure. The main findings were: (1) At both sampling intervals, CORT increased significantly in response to the first sampling and declined to baseline values in successive samples. (2) beta-END also increased significantly in response to the first sampling but remained elevated in successive samples. (3) Intensities of initial CORT and beta-END responses correlated positively with each other and with the baseline beta-END values. Feedback inhibition of CORT secretion with sustained elevation of beta-END titres suggests a moderate stress intensity of the repeated blood sampling procedures. In general, due to lack of short-term feedback inhibition, beta-END seems to reflect the effects of repeated administration of moderate intense stressors more closely than CORT. Effects of short-term repeated blood sampling on the secretion of corticosterone (CORT) and beta-endorphin (beta-END) were evaluated in male Wistar rats. Blood was drawn from the tail vein of conscious rats four times within 2 h both at the peak and trough period of the diurnal corticosterone secretion cycle. All rats were well accustomed to the procedure. The main findings were: (1) At both sampling intervals, CORT increased significantly in response to the first sampling and declined to baseline values in successive sample. (2) beta-END also increased significantly in response to the first sampling but remained elevated in successive samples. (3) Intensities of initial CORT and beta-END responses correlated positively with each other and with the baseline beta-END values. Feedback inhibition of CORT secretion with sustained elevation of beta-END titres suggests a moderate stress intensity of the repeated blood sampling procedures. In general, due to lack of short-term feedback inhibition, beta-END seems to reflect the effects of repeated administration of moderate intense stressors more closely than CORT. Effects of short-term repeated blood sampling on the secretion of corticosterone (CORT) and β-endorphin ( β-END) were evaluated in male Wistar rats. Blood was drawn from the tail vein of conscious rats four times within 2 h both at the peak and trough period of the diurnal corticosterone secretion cycle. All rats were well accustomed to the procedure. The main findings were: (1) At both sampling intervals, CORT increased significantly in response to the first sampling and declined to baseline values in successive samples. (2) β-END also increased significantly in response to the first sampling but remained elevated in successive samples. (3) Intensities of initial CORT and β-END responses correlated positively with each other and with the baseline β-END values. Feedback inhibition of CORT secretion with sustained elevation of β-END titres suggests a moderate stress intensity of the repeated blood sampling procedures. In general, due to lack of short-term feedback inhibition, β-END seems to reflect the effects of repeated administration of moderate intense stressors more closely than CORT. |
Author | Guerra, G Haemisch, A Furkert, J |
Author_xml | – sequence: 1 fullname: Haemisch, A – sequence: 2 fullname: Guerra, G – sequence: 3 fullname: Furkert, J |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/10780823$$D View this record in MEDLINE/PubMed |
BookMark | eNp9kMtKxTAQhoMoery8gAvNyl00lzaXpYg3EFyo65C002OlJ6lJuvDtrdaFILgaBr7vH-bfR9shBkDomNFzxmt9QSkXUiljlKa10oKaLbRiqtaEMaa20eoLIDPB99B-zm_zyipNd9Eeo7OiuVghf9m6sbjSx4Bjh5uYSt_EXCDNtwjxU8EhFuyhOAKhjWl87QMhGZoE31KJOMEIrkCL_RBji7PbjEMf1rgPOLmSD9FO54YMRz_zAL3cXD9f3ZGHx9v7q8sH0ggpClHQ1Ko1zrCOGaOlUNoD59C2XlYSjHec1lJ0SoGqwENVe9dRzYRRsqmMEAfobMkdU3yfIBe76XMDw-ACxClbaSrFa2ZmkC9gk2LOCTo7pn7j0odl1H41a_82O0snP-mT30D7S1mqnIGLBchuDfYtTinM3_4feboYnYvWrVOf7csTp0xQblituBSfFDaMuA |
CitedBy_id | crossref_primary_10_1016_j_heares_2017_03_005 crossref_primary_10_1016_S1385_299X_02_00185_X crossref_primary_10_1523_ENEURO_0424_21_2021 crossref_primary_10_1002_adma_201907478 crossref_primary_10_1016_j_ygcen_2016_10_015 crossref_primary_10_1097_WNR_0000000000001656 crossref_primary_10_1111_jpn_12004 crossref_primary_10_1007_s00360_008_0314_4 crossref_primary_10_1002_0471142301_ns0833s70 crossref_primary_10_1016_j_steroids_2018_03_004 crossref_primary_10_1016_j_yhbeh_2003_07_002 crossref_primary_10_1159_000524432 crossref_primary_10_1073_pnas_1806392115 crossref_primary_10_1152_ajpendo_00122_2005 crossref_primary_10_3390_ani10010165 crossref_primary_10_1016_S0196_9781_00_00345_4 crossref_primary_10_1016_S0016_6480_02_00620_2 crossref_primary_10_1016_j_physbeh_2010_01_021 |
ContentType | Journal Article |
Copyright | 1999 Royal Society of Medicine Press |
Copyright_xml | – notice: 1999 Royal Society of Medicine Press |
DBID | FBQ CGR CUY CVF ECM EIF NPM AAYXX CITATION 7X8 |
DOI | 10.1258/002367799780578309 |
DatabaseName | AGRIS Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef MEDLINE - Academic |
DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef MEDLINE - Academic |
DatabaseTitleList | MEDLINE CrossRef MEDLINE - Academic |
Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database – sequence: 3 dbid: FBQ name: AGRIS url: http://www.fao.org/agris/Centre.asp?Menu_1ID=DB&Menu_2ID=DB1&Language=EN&Content=http://www.fao.org/agris/search?Language=EN sourceTypes: Publisher |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Agriculture |
EISSN | 1758-1117 |
EndPage | 191 |
ExternalDocumentID | 10_1258_002367799780578309 10780823 10.1258_002367799780578309 US201302915726 |
Genre | Journal Article |
GroupedDBID | --- -MK .GJ 0R~ 0VX 18M 29L 35A 36B 3V. 4.4 53G 5GY 5I- 5I. 5RE 5VS 7RV 7X2 7X7 88A 88E 8AO 8FE 8FH 8FI 8FJ 8R4 8R5 8WZ A6W AACMV AACTG AADTT AAGMC AAJIQ AAJOX AAKGS AAMXZ AAQXH AATBZ AAUAS AAXGE AAXTJ AAYTG ABDWY ABFSF ABHKI ABJIS ABJOC ABLUO ABPGX ABPTK ABUWG ABVVC ABWRX ACARO ACFEJ ACFIC ACFMA ACGBL ACGFO ACGFS ACGZU ACJTF ACLFY ACLHI ACPRK ACPTO ACSBE ACUAV ACXMB ADBBV ADFPL ADTBJ ADWAY AECGH AECVZ AEDTQ AEKYL AENEX AEPTA AEWDL AEWLI AFDWH AFIEG AFKRA AFKRG AFNTS AFRAH AFTZB AFWIJ AGHDM AGWFA AGXYR AHMBA AHOKE AIOMO AJEFB AJMMQ AJQXQ AJUZI AJXAJ ALMA_UNASSIGNED_HOLDINGS AMCVQ AOSDY APEBS ARTOV ATCPS AYAKG BAWUL BBNVY BBRGL BENPR BHPHI BKEYQ BKIIM BPACV BPHCQ BVXVI BWJAD CAG CCPQU COF CORYS CQQTX CS3 DD- DE- DF0 DIK DN0 DO- DU5 E3Z EBS EJD EMB EMOBN EX3 F5P FBQ FHBDP FYUFA HCIFZ HMCUK HZ~ J8X LK8 M0K M0L M1P M4V M7P MV1 NAPCQ O9- OK1 P.B P.C P2P PQQKQ PROAC PSQYO Q1R Q2X QJJ ROL RWL SCNPE SFC SHG SPQ SPV SV3 TAE TR2 TRM UKHRP W8F WOW ZA5 ZXP ~KM AAEWN AAHBH AEMJX ALIPV ALTZF ACGZN CGR CUY CVF ECM EIF NPM AAYXX ALKWR CITATION H13 7X8 |
ID | FETCH-LOGICAL-c363t-7ec57d9a91f19986378be22eddb646e9ba20563f77e74ebe45baf0813976c4933 |
ISSN | 0023-6772 |
IngestDate | Sat Aug 17 00:26:15 EDT 2024 Wed Sep 11 14:09:57 EDT 2024 Thu May 23 23:03:06 EDT 2024 Tue Jul 16 20:50:09 EDT 2024 Wed Dec 27 19:18:57 EST 2023 |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 2 |
Keywords | WELFARE STRESS BETA-ENDORPHIN BLOOD-SAMPLING CORTICOSTERONE |
Language | English |
LinkModel | OpenURL |
MergedId | FETCHMERGED-LOGICAL-c363t-7ec57d9a91f19986378be22eddb646e9ba20563f77e74ebe45baf0813976c4933 |
Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
PMID | 10780823 |
PQID | 69472519 |
PQPubID | 23479 |
PageCount | 7 |
ParticipantIDs | proquest_miscellaneous_69472519 crossref_primary_10_1258_002367799780578309 pubmed_primary_10780823 sage_journals_10_1258_002367799780578309 fao_agris_US201302915726 |
PublicationCentury | 1900 |
PublicationDate | 1999-04-01 |
PublicationDateYYYYMMDD | 1999-04-01 |
PublicationDate_xml | – month: 04 year: 1999 text: 1999-04-01 day: 01 |
PublicationDecade | 1990 |
PublicationPlace | London, England |
PublicationPlace_xml | – name: London, England – name: England |
PublicationTitle | Laboratory animals (London) |
PublicationTitleAlternate | Lab Anim |
PublicationYear | 1999 |
Publisher | SAGE Publications |
Publisher_xml | – name: SAGE Publications |
SSID | ssj0021480 |
Score | 1.6435071 |
Snippet | Effects of short-term repeated blood sampling on the secretion of corticosterone (CORT) and beta-endorphin (beta-END) were evaluated in male Wistar rats. Blood... Effects of short-term repeated blood sampling on the secretion of corticosterone (CORT) and β-endorphin (β-END) were evaluated in male Wistar rats. Blood was... Effects of short-term repeated blood sampling on the secretion of corticosterone (CORT) and β-endorphin ( β-END) were evaluated in male Wistar rats. Blood was... |
SourceID | proquest crossref pubmed sage fao |
SourceType | Aggregation Database Index Database Publisher |
StartPage | 185 |
SubjectTerms | Animal Welfare Animals beta-Endorphin - blood beta-Endorphin - secretion blood plasma blood sampling Blood Specimen Collection - adverse effects Blood Specimen Collection - veterinary Chromatography, High Pressure Liquid - veterinary corticosterone Corticosterone - blood Corticosterone - secretion diurnal variation endorphins Feedback hormone secretion Male Radioimmunoassay - veterinary rats Rats - physiology Rats - psychology stress response Stress, Physiological - blood Stress, Physiological - etiology Stress, Physiological - veterinary Time Factors |
Title | Adaptation of corticosterone--but not beta-endorphin--secretion to repeated blood sampling in rats |
URI | https://journals.sagepub.com/doi/full/10.1258/002367799780578309 https://www.ncbi.nlm.nih.gov/pubmed/10780823 https://search.proquest.com/docview/69472519 |
Volume | 33 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lj9MwELa6ywUOiPeGpw8ckCpD7ThxfEGqYMuyrJYDrdRbsGMH9UBS5XHZX7_jPFt1eV6iKGpia-bzeKaebwah1zwBvSYzQ2ARhoRHKSUSdgoScUWFnumU2ibL9zI8W_HzdbCeTN7vZC3VlX6bXN3IK_kfrcIz0Ktjyf6DZoePwgO4B_3CFTQM17_S8dyobTX4fBBHwi8caaPIM0t0XU2zvHKZWIrYzOQg0U1GSucnNq-A11nYLdhi54S6_PVpqVx-eUdyUW2Np5Es3aDFHcmrbPPTVV3e6QYiR0vmGsi1_aUGcHyqbdH0Mxo7eS3qoqcLnY__PLTVCoaElZ4J4JNQiD1r2pa16FDDdkwjbVvzdLssbXt0HRhwFjSkBFfXXgjZdFwQkT-T43bVH9Fffo0Xq4uLeHm6Xh6hW0zIwAXfHz9_GQJuCPVaClI3z440BWO8OxxhzzE5SlV-U8yxl-_XuCDLe-huFzvgeQuE-2hiswfozvxH0dVPsQ_R9xESOE_xISQwQAL_ChK4ynEPCdxAAveQwJsMO0g8QqvF6fLDGemaaJDED_2KCJsEwkglaerolKEvIm0Zs8bokIdWasXAB_ZTIazgsKJ5oFUKfqLzUxMuff8xOs5giicIM6qosalJLEt5arnSyljDA6aoDk2iPDTtJRhv21opsYsxQd7xobw9dAJCjhUIqYxX31hzhC5pIFjooVe95GOHWZcHmNm8LuNQcuG41h560ipkZyD4csR8D71xGoq7ZVr-ZgZP_zjMM3R7BP5zdFwVtX0BTmilXzZIuwb6gYLt |
link.rule.ids | 315,786,790,27957,27958 |
linkProvider | Flying Publisher |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Adaptation+of+corticosterone-but+not+beta-endorphin-secretion+to+repeated+blood+sampling+in+rats&rft.jtitle=Laboratory+animals+%28London%29&rft.au=Haemisch%2C+A&rft.au=Guerra%2C+G&rft.au=Furkert%2C+J&rft.date=1999-04-01&rft.issn=0023-6772&rft.volume=33&rft.issue=2&rft.spage=185&rft.epage=191&rft_id=info:doi/10.1258%2F002367799780578309&rft.externalDBID=NO_FULL_TEXT |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0023-6772&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0023-6772&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0023-6772&client=summon |