Functional connectivity analysis and prediction of cognitive change after carotid artery stenting

• Published in: Journal of neurosurgery Vol. 131; no. 6; p. 1709
• Main Authors: Tani, Naoki, Yaegaki, Takahide, Nishino, Akio, Fujimoto, Kenta, Hashimoto, Hiroyuki, Horiuchi, Kaoru, Nishiguchi, Mitsuhisa, Kishima, Haruhiko
• Format: Journal Article
• Language: English
• Published: United States 01.12.2019
• Subjects: Aged; Carotid Artery, External - diagnostic imaging; Carotid Artery, External - surgery; Carotid Stenosis - diagnostic imaging; Carotid Stenosis - surgery; Cerebral Revascularization - instrumentation; Cerebral Revascularization - trends; Cognition - physiology; Humans; Magnetic Resonance Imaging - trends; Male; Middle Aged; Nerve Net - diagnostic imaging; Predictive Value of Tests; Stents; FIQ = full-scale IQ; WMS-R = Wechsler Memory Scale–Revised; MNI = Montreal Neurological Institute; CAS = carotid artery stenting; pDMN = posterior part of DMN; cognitive change; NASCET = North American Symptomatic Carotid Endarterectomy; FC = functional connectivity; ICA = internal carotid artery; vascular disorders; VIQ = verbal IQ; carotid artery stenting; SFG = superior frontal gyrus; rs-fMRI = resting-state functional MRI; functional connectivity; working memory; PIQ = performance IQ; WAIS-III = Wechsler Adult Intelligence Scale III; aDMN = anterior part of DMN; DMN = default mode network; default mode network; MFG = middle frontal gyrus
• ISSN: 1933-0693
• DOI: 10.3171/2018.7.JNS18404

The neurocognitive course of patients who have undergone cerebral revascularization has been the subject of many studies, and the reported effects of carotid artery stenting (CAS) on cognitive function have varied from study to study. The authors hypothesized that cognitive amelioration after CAS is...