Comprehensive insights into the multifaceted roles of the transient receptor potential vanilloid 1 channel in the digestive system

• Published in: Life sciences (1973) Vol. 334; p. 122207
• Main Authors: Wang, Juan, Kumar, Pavitra, Engelmann, Cornelius
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01.12.2023
• Subjects: Calcium; Capsaicin; Digestive diseases; digestive system; domain; family; heart; homeostasis; human health; mammals; metastasis; nervous system; pain; transient receptor potential vanilloid channels; TRPV1; Digestive diseases; TRPV1; Calcium; Capsaicin

The transient receptor potential vanilloid (TRPV) channel, a family of calcium transporters comprising six distinct members (TRPV1–6), takes on a paramount role in maintaining intracellular Ca2+ homeostasis in mammalian cells. Notably, TRPV1, among its counterparts, has emerged as the subject of ext...