Glucagon-like peptide 1 treatment reverses vascular remodelling by downregulating matrix metalloproteinase 1 expression through inhibition of the ERK1/2/NF-κB signalling pathway - Fan, Shao-Hua; Xiong, Qian-Feng; Wang, Lei; Zhang, Li-Hui; Shi, Ya-Wei (Molecular and cellular endocrinology, 2020)
Keywords: agonists; collagen; diastolic blood pressure; ERK1/2; extracellular matrix; GLP-1; glucagon-like peptide 1; hypertension; interstitial collagenase; MMP1; NF-κB; noninsulin-dependent diabetes mellitus; rats; smooth muscle; systolic blood pressure; therapeutics; Vascular remodelling; SBP; T2DM; GLP-1; WKY; MMP1; RAS; AT1R; HR; BP; ECM; DPP4; NF-κB; FAK; ERK1/2; Vascular remodelling; DBP; PI3K; RASMC; VSMC; SHR; AngII; p38MAPK; GLP-1R