Eumycetoma and actinomycetoma - an update on causative agents, epidemiology, pathogenesis, diagnostics and therapy

• Published in: Journal of the European Academy of Dermatology and Venereology Vol. 29; no. 10; pp. 1873 - 1883
• Main Authors: Nenoff, P., van de Sande, W.W.J., Fahal, A.H., Reinel, D., Schöfer, H.
• Format: Journal Article
• Language: English
• Published: England Blackwell Publishing Ltd 01.10.2015
• Subjects: Actinomycetales; Actinomycetales Infections - complications; Amputation; Animals; Anti-Bacterial Agents - therapeutic use; Antifungal Agents - therapeutic use; Cytokines - metabolism; Debridement; Diagnosis, Differential; Humans; Inflammation - metabolism; Inflammation - microbiology; Itraconazole - therapeutic use; Madurella; Mycetoma - diagnosis; Mycetoma - epidemiology; Mycetoma - metabolism; Mycetoma - microbiology; Mycetoma - therapy; Naphthalenes - therapeutic use; Triazoles - therapeutic use

Mycetoma is a chronic putrid infection of the cutaneous and subcutaneous tissue concerning predominantly the feet, and more rarely other body parts. Mycetoma can be caused by both fungi (eumycetoma) and bacteria (actinomycetoma). Mode of infection is an inoculation of the causative microorganism via...