In vitro exposure of pig neonatal isletlike cell clusters to human blood - Nagaraju, Santosh; Bertera, Suzanne; Tanaka, Takayuki; Hara, Hidetaka; Rayat, Gina R.; Wijkstrom, Martin; Ayares, David; Trucco, Massimo; Cooper, David K. C.; Bottino, Rita (Xenotransplantation (Københaven), 2015)
Keywords: Animals; Animals, Genetically Modified; Animals, Newborn; Antigens, CD - genetics; Antigens, CD - immunology; Apyrase - genetics; Apyrase - immunology; Blood - immunology; Blood Coagulation; Complement Activation; diabetes mellitus; Diabetes Mellitus - therapy; Galactosyltransferases - deficiency; Galactosyltransferases - genetics; Galactosyltransferases - immunology; Gene Knockout Techniques; genetically engineered; Humans; In Vitro Techniques; instant blood-mediated inflammatory reaction; islets; Islets of Langerhans Transplantation - adverse effects; Islets of Langerhans Transplantation - immunology; Islets of Langerhans Transplantation - pathology; Membrane Cofactor Protein - genetics; Membrane Cofactor Protein - immunology; neonatal; pigs; Recombinant Proteins - genetics; Recombinant Proteins - immunology; Sus scrofa; Transplantation, Heterologous - adverse effects; Transplantation, Heterologous - methods; xenotransplantation; pigs; genetically engineered; islets; neonatal; instant blood-mediated inflammatory reaction; diabetes mellitus; xenotransplantation