Frequency of serological markers of rheumatoid arthritis in patients with IgA anti‐β2 glycoprotein I antibodies

Aim To determine the frequency of serological markers of RA in patients with anti‐β2 glycoprotein I antibodies (aβ2GPI) of IgA isotype. Material and Methods A retrospective study was conducted on 67 patients with aβ2GPI‐IgA. Ninety healthy blood donors (HBD) were used as a control group. IgG anti‐cy...

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Published inJournal of clinical laboratory analysis Vol. 36; no. 7; pp. e24537 - n/a
Main Authors Melayah, Sarra, Ghozzi, Mariem, Mankaï, Amani, Mechi, Fatma, Ghedira, Ibtissem
Format Journal Article
LanguageEnglish
Published United States John Wiley & Sons, Inc 01.07.2022
John Wiley and Sons Inc
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Abstract Aim To determine the frequency of serological markers of RA in patients with anti‐β2 glycoprotein I antibodies (aβ2GPI) of IgA isotype. Material and Methods A retrospective study was conducted on 67 patients with aβ2GPI‐IgA. Ninety healthy blood donors (HBD) were used as a control group. IgG anti‐cyclic citrullinated peptides antibodies (CCP‐Ab) and rheumatoid factors (RF) IgG, IgA, and IgM were detected by enzyme‐linked immunosorbent assay (ELISA). Results Seventeen patients and eight HBD had CCP‐Ab and/or RF (25.4% vs. 8.9%, p = 0.005, CI 95% [14.95; 35.79], odds ratio = 3.5). The frequency of CCP‐Ab was significantly higher in patients than in healthy subjects (14.9% vs. 3.3%, p = 0.009). IgA isotype of RF was significantly higher in patients than in controls (7.5% vs. 0%, p = 0.02). In male patients, CCP‐Ab and/or RF were more frequent than in healthy male subjects (37.5% vs. 11.8%, p = 0.02). In patients, no correlation was found between the levels of aβ2GPI‐IgA and CCP‐Ab (r = 0.082, p = 0.51). There was no correlation between the level aβ2GPI‐IgA and the level of the isotypes of RF (IgG, IgA, and IgM) in patients (r = 0.1, p = 0.37; r = 0.17, p = 0.17 and r = 0.07, p = 0.59 respectively). Conclusion Frequencies of CCP‐Ab and RF are high in patients with aβ2GPI‐IgA suggesting that these patients are susceptible to developing RA. Frequency of CCP‐Ab and RF in patients with IgA anti‐β2 glycoprotein I antibodies.
AbstractList AimTo determine the frequency of serological markers of RA in patients with anti‐β2 glycoprotein I antibodies (aβ2GPI) of IgA isotype.Material and MethodsA retrospective study was conducted on 67 patients with aβ2GPI‐IgA. Ninety healthy blood donors (HBD) were used as a control group. IgG anti‐cyclic citrullinated peptides antibodies (CCP‐Ab) and rheumatoid factors (RF) IgG, IgA, and IgM were detected by enzyme‐linked immunosorbent assay (ELISA).ResultsSeventeen patients and eight HBD had CCP‐Ab and/or RF (25.4% vs. 8.9%, p = 0.005, CI 95% [14.95; 35.79], odds ratio = 3.5). The frequency of CCP‐Ab was significantly higher in patients than in healthy subjects (14.9% vs. 3.3%, p = 0.009). IgA isotype of RF was significantly higher in patients than in controls (7.5% vs. 0%, p = 0.02). In male patients, CCP‐Ab and/or RF were more frequent than in healthy male subjects (37.5% vs. 11.8%, p = 0.02). In patients, no correlation was found between the levels of aβ2GPI‐IgA and CCP‐Ab (r = 0.082, p = 0.51). There was no correlation between the level aβ2GPI‐IgA and the level of the isotypes of RF (IgG, IgA, and IgM) in patients (r = 0.1, p = 0.37; r = 0.17, p = 0.17 and r = 0.07, p = 0.59 respectively).ConclusionFrequencies of CCP‐Ab and RF are high in patients with aβ2GPI‐IgA suggesting that these patients are susceptible to developing RA.
Aim To determine the frequency of serological markers of RA in patients with anti‐β2 glycoprotein I antibodies (aβ2GPI) of IgA isotype. Material and Methods A retrospective study was conducted on 67 patients with aβ2GPI‐IgA. Ninety healthy blood donors (HBD) were used as a control group. IgG anti‐cyclic citrullinated peptides antibodies (CCP‐Ab) and rheumatoid factors (RF) IgG, IgA, and IgM were detected by enzyme‐linked immunosorbent assay (ELISA). Results Seventeen patients and eight HBD had CCP‐Ab and/or RF (25.4% vs. 8.9%, p = 0.005, CI 95% [14.95; 35.79], odds ratio = 3.5). The frequency of CCP‐Ab was significantly higher in patients than in healthy subjects (14.9% vs. 3.3%, p = 0.009). IgA isotype of RF was significantly higher in patients than in controls (7.5% vs. 0%, p = 0.02). In male patients, CCP‐Ab and/or RF were more frequent than in healthy male subjects (37.5% vs. 11.8%, p = 0.02). In patients, no correlation was found between the levels of aβ2GPI‐IgA and CCP‐Ab (r = 0.082, p = 0.51). There was no correlation between the level aβ2GPI‐IgA and the level of the isotypes of RF (IgG, IgA, and IgM) in patients (r = 0.1, p = 0.37; r = 0.17, p = 0.17 and r = 0.07, p = 0.59 respectively). Conclusion Frequencies of CCP‐Ab and RF are high in patients with aβ2GPI‐IgA suggesting that these patients are susceptible to developing RA. Frequency of CCP‐Ab and RF in patients with IgA anti‐β2 glycoprotein I antibodies.
To determine the frequency of serological markers of RA in patients with anti-β2 glycoprotein I antibodies (aβ2GPI) of IgA isotype. A retrospective study was conducted on 67 patients with aβ2GPI-IgA. Ninety healthy blood donors (HBD) were used as a control group. IgG anti-cyclic citrullinated peptides antibodies (CCP-Ab) and rheumatoid factors (RF) IgG, IgA, and IgM were detected by enzyme-linked immunosorbent assay (ELISA). Seventeen patients and eight HBD had CCP-Ab and/or RF (25.4% vs. 8.9%, p = 0.005, CI 95% [14.95; 35.79], odds ratio = 3.5). The frequency of CCP-Ab was significantly higher in patients than in healthy subjects (14.9% vs. 3.3%, p = 0.009). IgA isotype of RF was significantly higher in patients than in controls (7.5% vs. 0%, p = 0.02). In male patients, CCP-Ab and/or RF were more frequent than in healthy male subjects (37.5% vs. 11.8%, p = 0.02). In patients, no correlation was found between the levels of aβ2GPI-IgA and CCP-Ab (r = 0.082, p = 0.51). There was no correlation between the level aβ2GPI-IgA and the level of the isotypes of RF (IgG, IgA, and IgM) in patients (r = 0.1, p = 0.37; r = 0.17, p = 0.17 and r = 0.07, p = 0.59 respectively). Frequencies of CCP-Ab and RF are high in patients with aβ2GPI-IgA suggesting that these patients are susceptible to developing RA.
Frequency of CCP‐Ab and RF in patients with IgA anti‐β2 glycoprotein I antibodies.
Author Melayah, Sarra
Mechi, Fatma
Ghedira, Ibtissem
Ghozzi, Mariem
Mankaï, Amani
AuthorAffiliation 5 High School of Sciences and Techniques of Health Tunis El Manar University Tunis Tunisia
3 LR12SP11, Biochemistry Department Sahloul University Hospital Sousse Tunisia
1 Laboratory of Immunology Farhat Hached Hospital Sousse Tunisia
2 Department of Immunology, Faculty of Pharmacy Monastir University Monastir Tunisia
6 Research Unit "Obesity: Etiopathology and Treatment, UR18ES01" National Institute of Nutrition and Food Technology Tunis Tunisia
4 Research Unit "Epidemiology and Immunogenetics of Viral Infections, LR14SP02" Sahloul University Hospital Sousse Tunisia
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– name: 5 High School of Sciences and Techniques of Health Tunis El Manar University Tunis Tunisia
– name: 6 Research Unit "Obesity: Etiopathology and Treatment, UR18ES01" National Institute of Nutrition and Food Technology Tunis Tunisia
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CitedBy_id crossref_primary_10_1007_s00404_022_06892_8
Cites_doi 10.1007/s00296-008-0614-8
10.1038/s41584-018-0070-0
10.1007/s00281-017-0630-4
10.1002/art.38131
10.1097/BOR.0000000000000708
10.1016/j.patbio.2011.07.003
10.1080/08916930601061538
10.1016/j.semarthrit.2020.10.003
10.1002/jcla.24249
10.1002/art.22802
10.1002/jcla.23217
10.1093/rheumatology/kev226
10.1016/j.blre.2019.100610
10.1155/2017/4835189
10.3390/cells8070700
10.3390/ijms23020905
10.3389/fimmu.2021.741369
10.1007/s12016-016-8565-4
10.1016/j.molmed.2015.02.006
10.1136/ard.2007.082669
10.1038/s41584-021-00585-3
10.1111/j.1538-7836.2006.01753.x
10.3390/ijms21238972
10.1016/j.jbspin.2019.01.005
10.1093/rheumatology/keab585
10.3389/fimmu.2021.726820
10.3389/fimmu.2019.01031
10.1016/j.immuni.2017.02.006
10.1016/j.autrev.2019.102352
10.1016/j.autrev.2016.01.001
10.1186/s13075-016-0940-2
10.1002/jcla.21723
10.1007/s11926-014-0472-1
10.1007/s00296-007-0351-4
10.1007/s12026-017-8899-x
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Issue 7
Keywords antiphospholipid syndrome
rheumatoid factors
anti-cyclic citrullinated peptides antibodies
rheumatoid arthritis
anti-β2 glycoprotein I antibodies
Language English
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References 2019; 8
2012; 60
2015; 17
2017; 2017
2013; 65
2019; 10
2006; 39
2017; 65
2017; 46
2015; 54
2020; 39
2022; 23
2019; 18
2006; 4
2020; 34
2002; 80
2020; 32
2016; 18
2007; 56
2021; 51
2016; 15
2021; 13
2017; 53
2021; 12
2015; 29
2019; 86
2017; 39
2008; 29
2021; 17
2015; 21
2008; 67
2022; 36
2020; 21
2021; 61
2018; 14
2007; 27
e_1_2_7_6_1
e_1_2_7_5_1
Shapiro SC (e_1_2_7_12_1) 2021; 13
e_1_2_7_4_1
e_1_2_7_3_1
e_1_2_7_9_1
e_1_2_7_8_1
e_1_2_7_7_1
e_1_2_7_19_1
e_1_2_7_18_1
e_1_2_7_17_1
e_1_2_7_16_1
e_1_2_7_2_1
e_1_2_7_15_1
e_1_2_7_14_1
e_1_2_7_13_1
e_1_2_7_11_1
e_1_2_7_10_1
e_1_2_7_26_1
e_1_2_7_27_1
e_1_2_7_29_1
e_1_2_7_30_1
e_1_2_7_25_1
e_1_2_7_31_1
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e_1_2_7_32_1
e_1_2_7_23_1
e_1_2_7_33_1
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e_1_2_7_34_1
e_1_2_7_21_1
e_1_2_7_35_1
e_1_2_7_20_1
e_1_2_7_36_1
e_1_2_7_37_1
e_1_2_7_38_1
Fakhfakh R (e_1_2_7_28_1) 2002; 80
References_xml – volume: 2017
  start-page: 4835189
  year: 2017
  article-title: Intestinal dysbiosis and rheumatoid arthritis: a link between gut microbiota and the pathogenesis of rheumatoid arthritis
  publication-title: J Immunol Res
– volume: 53
  start-page: 1
  issue: 1
  year: 2017
  end-page: 13
  article-title: Anti‐phospholipid antibodies and smoking: an overview
  publication-title: Clin Rev Allergy Immunol
– volume: 65
  start-page: 524
  issue: 2
  year: 2017
  end-page: 531
  article-title: Anti‐mutated citrullinated vimentin antibodies in antiphospholipid syndrome: diagnostic value and relationship with clinical features
  publication-title: Immunol Res
– volume: 32
  start-page: 289
  issue: 3
  year: 2020
  end-page: 296
  article-title: Preclinical rheumatoid arthritis and rheumatoid arthritis prevention
  publication-title: Curr Opin Rheumatol
– volume: 51
  start-page: 20
  issue: 1
  year: 2021
  end-page: 27
  article-title: Beta‐2‐glycoprotein‐I IgA antibodies predict coronary plaque progression in rheumatoid arthritis
  publication-title: Semin Arthritis Rheum
– volume: 39
  year: 2020
  article-title: The role of beta‐2‐glycoprotein I in health and disease associating structure with function: more than just APS
  publication-title: Blood Rev
– volume: 29
  start-page: 59
  issue: 1
  year: 2008
  end-page: 62
  article-title: Value of anti‐mutated citrullinated vimentin antibodies in diagnosing rheumatoid arthritis
  publication-title: Rheumatol Int
– volume: 27
  start-page: 1125
  issue: 12
  year: 2007
  end-page: 1130
  article-title: Diagnostic performances of anti‐cyclic citrullinated peptide antibodies in rheumatoid arthritis
  publication-title: Rheumatol Int
– volume: 56
  start-page: 2687
  issue: 8
  year: 2007
  end-page: 2697
  article-title: Anti‐beta2‐glycoprotein I antibodies induce monocyte release of tumor necrosis factor alpha and tissue factor by signal transduction pathways involving lipid rafts
  publication-title: Arthritis Rheum
– volume: 39
  start-page: 395
  issue: 4
  year: 2017
  end-page: 408
  article-title: Genetics of rheumatoid arthritis susceptibility, severity, and treatment response
  publication-title: Semin Immunopathol
– volume: 67
  start-page: 1529
  issue: 11
  year: 2008
  end-page: 1534
  article-title: Cigarette smoking, disease severity and autoantibody expression in African Americans with recent‐onset rheumatoid arthritis
  publication-title: Ann Rheum Dis
– volume: 34
  issue: 6
  year: 2020
  article-title: IgA is the predominant isotype of anti‐β2 glycoprotein I antibodies in rheumatoid arthritis
  publication-title: J Clin Lab Anal
– volume: 46
  start-page: 183
  issue: 2
  year: 2017
  end-page: 196
  article-title: Immunopathogenesis of rheumatoid arthritis
  publication-title: Immunity
– volume: 4
  start-page: 295
  issue: 2
  year: 2006
  end-page: 306
  article-title: International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS)
  publication-title: J Thromb Haemost
– volume: 18
  issue: 9
  year: 2019
  article-title: Antiphospholipid syndrome's genetic and epigenetic aspects
  publication-title: Autoimmun Rev
– volume: 15
  start-page: 354
  issue: 4
  year: 2016
  end-page: 374
  article-title: Smoke and autoimmunity: the fire behind the disease
  publication-title: Autoimmun Rev
– volume: 17
  start-page: 224
  issue: 4
  year: 2021
  end-page: 237
  article-title: The gut‐joint axis in rheumatoid arthritis
  publication-title: Nat Rev Rheumatol
– volume: 13
  issue: 5
  year: 2021
  article-title: Biomarkers in rheumatoid arthritis
  publication-title: Cureus
– volume: 65
  start-page: 3186
  issue: 12
  year: 2013
  end-page: 3193
  article-title: Value of isolated IgA anti‐β2‐glycoprotein I positivity in the diagnosis of the antiphospholipid syndrome
  publication-title: Arthritis Rheum
– volume: 10
  year: 2019
  article-title: The IgA isotype of anti‐β2 glycoprotein I antibodies recognizes epitopes in domains 3, 4, and 5 that are located in a lateral zone of the molecule (L‐shaped)
  publication-title: Front Immunol
– volume: 8
  start-page: 700
  issue: 7
  year: 2019
  article-title: Mucosa‐environment interactions in the pathogenesis of rheumatoid arthritis
  publication-title: Cell
– volume: 39
  start-page: 683
  issue: 8
  year: 2006
  end-page: 690
  article-title: Microparticles as mediators of cellular cross‐talk in inflammatory disease
  publication-title: Autoimmunity
– volume: 54
  start-page: 2042
  issue: 11
  year: 2015
  end-page: 2050
  article-title: Examining the prevalence of non‐criteria anti‐phospholipid antibodies in patients with anti‐phospholipid syndrome: a systematic review
  publication-title: Rheumatology (Oxford)
– volume: 14
  start-page: 542
  issue: 9
  year: 2018
  end-page: 557
  article-title: Rheumatoid arthritis and the mucosal origins hypothesis: protection turns to destruction
  publication-title: Nat Rev Rheumatol
– volume: 29
  start-page: 32
  issue: 1
  year: 2015
  end-page: 36
  article-title: High frequency of antiphospholipid antibodies in primary biliary cirrhosis
  publication-title: J Clin Lab Anal
– volume: 17
  start-page: 472
  issue: 1
  year: 2015
  article-title: The role of the gut microbiota in the pathogenesis of antiphospholipid syndrome
  publication-title: Curr Rheumatol Rep
– volume: 36
  issue: 3
  year: 2022
  article-title: Frequency of serological markers of rheumatoid arthritis in adult patients with active celiac disease
  publication-title: J Clin Lab Anal
– volume: 12
  year: 2021
  article-title: Antiphospholipid antibody assays in 2021: looking for a predictive value in addition to a diagnostic one
  publication-title: Front Immunol
– volume: 23
  start-page: 905
  issue: 2
  year: 2022
  article-title: Rheumatoid arthritis: pathogenic roles of diverse immune cells
  publication-title: Int J Mol Sci
– volume: 21
  issue: 23
  year: 2020
  article-title: The weight of IgA anti‐β2glycoprotein I in the antiphospholipid syndrome pathogenesis: closing the gap of seronegative antiphospholipid syndrome
  publication-title: Int J Mol Sci
– volume: 60
  start-page: 291
  issue: 5
  year: 2012
  end-page: 295
  article-title: Anti‐cardiolipin and anti‐beta 2‐glycoprotein I antibodies in celiac disease
  publication-title: Pathol Biol (Paris)
– volume: 61
  start-page: 2124
  year: 2021
  end-page: 2131
  article-title: RETRO study group. IgA anti‐citrullinated protein antibodies (IgA ACPA) are associated with flares during DMARD tapering in rheumatoid arthritis
  publication-title: Rheumatology (Oxford)
– volume: 86
  start-page: 562
  issue: 5
  year: 2019
  end-page: 567
  article-title: Pathogenic effects of anti‐citrullinated protein antibodies in rheumatoid arthritis – role for glycosylation
  publication-title: Joint Bone Spine
– volume: 12
  year: 2021
  article-title: Evaluation of the diagnostic value of non‐criteria antibodies for antiphospholipid syndrome patients in a Chinese cohort
  publication-title: Front Immunol
– volume: 80
  start-page: 350
  year: 2002
  end-page: 356
  article-title: Tobacco use in Tunisia: behaviour and awareness
  publication-title: Bull World Health Organ
– volume: 18
  start-page: 43
  year: 2016
  article-title: Rheumatoid factor isotypes in relation to antibodies against citrullinated peptides and carbamylated proteins before the onset of rheumatoid arthritis
  publication-title: Arthritis Res Ther
– volume: 21
  start-page: 233
  issue: 4
  year: 2015
  end-page: 244
  article-title: Autoimmune host‐microbiota interactions at barrier sites and beyond
  publication-title: Trends Mol Med
– ident: e_1_2_7_20_1
  doi: 10.1007/s00296-008-0614-8
– ident: e_1_2_7_33_1
  doi: 10.1038/s41584-018-0070-0
– ident: e_1_2_7_18_1
  doi: 10.1007/s00281-017-0630-4
– ident: e_1_2_7_23_1
  doi: 10.1002/art.38131
– ident: e_1_2_7_31_1
  doi: 10.1097/BOR.0000000000000708
– ident: e_1_2_7_8_1
  doi: 10.1016/j.patbio.2011.07.003
– ident: e_1_2_7_14_1
  doi: 10.1080/08916930601061538
– ident: e_1_2_7_19_1
  doi: 10.1016/j.semarthrit.2020.10.003
– ident: e_1_2_7_29_1
  doi: 10.1002/jcla.24249
– ident: e_1_2_7_16_1
  doi: 10.1002/art.22802
– ident: e_1_2_7_10_1
  doi: 10.1002/jcla.23217
– ident: e_1_2_7_5_1
  doi: 10.1093/rheumatology/kev226
– ident: e_1_2_7_2_1
  doi: 10.1016/j.blre.2019.100610
– volume: 13
  start-page: e15063
  issue: 5
  year: 2021
  ident: e_1_2_7_12_1
  article-title: Biomarkers in rheumatoid arthritis
  publication-title: Cureus
  contributor:
    fullname: Shapiro SC
– ident: e_1_2_7_34_1
  doi: 10.1155/2017/4835189
– ident: e_1_2_7_36_1
  doi: 10.3390/cells8070700
– ident: e_1_2_7_11_1
  doi: 10.3390/ijms23020905
– ident: e_1_2_7_7_1
  doi: 10.3389/fimmu.2021.741369
– ident: e_1_2_7_27_1
  doi: 10.1007/s12016-016-8565-4
– ident: e_1_2_7_38_1
  doi: 10.1016/j.molmed.2015.02.006
– ident: e_1_2_7_26_1
  doi: 10.1136/ard.2007.082669
– ident: e_1_2_7_35_1
  doi: 10.1038/s41584-021-00585-3
– ident: e_1_2_7_4_1
  doi: 10.1111/j.1538-7836.2006.01753.x
– ident: e_1_2_7_6_1
  doi: 10.3390/ijms21238972
– ident: e_1_2_7_13_1
  doi: 10.1016/j.jbspin.2019.01.005
– ident: e_1_2_7_32_1
  doi: 10.1093/rheumatology/keab585
– volume: 80
  start-page: 350
  year: 2002
  ident: e_1_2_7_28_1
  article-title: Tobacco use in Tunisia: behaviour and awareness
  publication-title: Bull World Health Organ
  contributor:
    fullname: Fakhfakh R
– ident: e_1_2_7_3_1
  doi: 10.3389/fimmu.2021.726820
– ident: e_1_2_7_22_1
  doi: 10.3389/fimmu.2019.01031
– ident: e_1_2_7_15_1
  doi: 10.1016/j.immuni.2017.02.006
– ident: e_1_2_7_17_1
  doi: 10.1016/j.autrev.2019.102352
– ident: e_1_2_7_25_1
  doi: 10.1016/j.autrev.2016.01.001
– ident: e_1_2_7_30_1
  doi: 10.1186/s13075-016-0940-2
– ident: e_1_2_7_9_1
  doi: 10.1002/jcla.21723
– ident: e_1_2_7_37_1
  doi: 10.1007/s11926-014-0472-1
– ident: e_1_2_7_21_1
  doi: 10.1007/s00296-007-0351-4
– ident: e_1_2_7_24_1
  doi: 10.1007/s12026-017-8899-x
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Snippet Aim To determine the frequency of serological markers of RA in patients with anti‐β2 glycoprotein I antibodies (aβ2GPI) of IgA isotype. Material and Methods A...
To determine the frequency of serological markers of RA in patients with anti-β2 glycoprotein I antibodies (aβ2GPI) of IgA isotype. A retrospective study was...
AimTo determine the frequency of serological markers of RA in patients with anti‐β2 glycoprotein I antibodies (aβ2GPI) of IgA isotype.Material and MethodsA...
AIMTo determine the frequency of serological markers of RA in patients with anti-β2 glycoprotein I antibodies (aβ2GPI) of IgA isotype. MATERIAL AND METHODSA...
Frequency of CCP‐Ab and RF in patients with IgA anti‐β2 glycoprotein I antibodies.
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StartPage e24537
SubjectTerms Antibodies
antiphospholipid syndrome
anti‐cyclic citrullinated peptides antibodies
anti‐β2 glycoprotein I antibodies
Autoimmune diseases
Blood donors
Citrulline
Disease
Enzyme-linked immunosorbent assay
Females
Glycoprotein I
Glycoproteins
Hepatitis
Immunoglobulin A
Immunoglobulin G
Immunoglobulin M
Isotypes
Lupus
Males
Peptides
Pregnancy
Rheumatoid arthritis
rheumatoid factors
Serology
Thrombosis
Tumor necrosis factor-TNF
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Title Frequency of serological markers of rheumatoid arthritis in patients with IgA anti‐β2 glycoprotein I antibodies
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