Optimization of immunization procedure for SWCNTs‐based subunit vaccine with mannose modification against spring viraemia of carp virus in common carp

• Published in: Journal of fish diseases Vol. 44; no. 12; pp. 1925 - 1936
• Main Authors: Gong, Yu‐Ming, Zhang, Chen, Li, Yang, Chen, Guo, Wang, Gao‐Xue, Zhu, Bin
• Format: Journal Article
• Language: English
• Published: Oxford Blackwell Publishing Ltd 01.12.2021
• Subjects: carbon nanotubes; Carp; Carp sprivivirus; CD4 antigen; common carp; Cyprinus carpio; Density; Disease control; Fish; Flow charts; Freshwater fishes; Gene expression; Genes; Glycoproteins; Immersion; immersion vaccination; Immunization; immunization procedure; interleukin-10; Juveniles; Major histocompatibility complex; Mannans; Mannose; Nanotechnology; Nanotubes; Optimization; Procedures; Single wall carbon nanotubes; spring viraemia of carp virus; Submerging; subunit vaccines; Survival; Vaccination; Vaccines; Viremia; Viruses

Immersion vaccination of single‐walled carbon nanotubes loaded with mannose‐modified glycoprotein (SWCNTs‐MG) vaccine has been proved to be effective in preventing spring viraemia of carp virus (SVCV). Immunization procedure has immense consequence on the immune effect of the immersion vaccine. Howe...