Association of factor V Leiden, Janus kinase 2, prothrombin, and MTHFR mutations with primary Budd-Chiari syndrome in Egyptian patients

• Published in: Journal of gastroenterology and hepatology Vol. 31; no. 1; pp. 235 - 240
• Main Authors: El Sebay, Hatem M, Safan, Manal A, Daoud, Ashraf A, Tayel, Safaa I, A Nouh, Mohamed, El Shafie, Shymaa
• Format: Journal Article
• Language: English
• Published: Australia Blackwell Publishing Ltd 01.01.2016
• Subjects: Adult; BCS; Budd-Chiari Syndrome - genetics; Egypt; Factor V - genetics; factor V Leiden; Female; Genetic Association Studies; Humans; JAK2; Janus Kinase 2 - genetics; Male; Methylenetetrahydrofolate Reductase (NADPH2) - genetics; MTHFR; Mutation; prothrombin; Prothrombin - genetics; Egypt; factor V Leiden; MTHFR; BCS; JAK2; prothrombin

Background and Aim Budd–Chiari syndrome (BCS) is defined as obstruction of hepatic venous outflow anywhere from the small hepatic veins to the suprahepatic inferior vena cava. The pathogenesis of BCS is still not fully understood. This study aimed to evaluate the association of factor V Leiden (FVL)...