Reducing pressure and increasing peak capacity by incorporating an adaptable flow stream splitting platform to high‐performance liquid chromatography columns: A study on C18 silica‐based monoliths

• Published in: Journal of separation science Vol. 46; no. 13; pp. e2200755 - n/a
• Main Author: Shalliker, Ross Andrew
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 01.07.2023
• Subjects: C18 silica monoliths; chromatography; Efficiency; high‐performance liquid chromatography; Liquid chromatography; Outlet flow; Propylbenzene; Radial flow; radial flow stream splitting; Retrofitting; Sensitivity; Splitting; high-performance liquid chromatography; C18 silica monoliths; chromatography; radial flow stream splitting

In this study, an adaptable end‐column platform was fitted to a commercially available monolith, which enabled the column to be fitted with a flow‐splitting device. A variety of flow‐splitting adapters could be incorporated into the platform, and in this study, a radial flow stream splitter was util...