Acupuncture Medical Therapy and its Underlying Mechanisms: A Systematic Review

As a traditional Chinese alternative health care approach, acupuncture is gaining increasing attention and reputation in China and overseas. While becoming increasingly popular globally, some consumers and professionals still know little about the therapy and underlying mechanisms of acupuncture. Du...

Full description

Saved in:
Bibliographic Details
Published inThe American journal of Chinese medicine (1979) Vol. 49; no. 1; p. 1
Main Authors Wen, Jingyi, Chen, Xi, Yang, Yong, Liu, Jianxin, Li, Enyin, Liu, Jiayou, Zhou, Ziwei, Wu, Weihua, He, Kai
Format Journal Article
LanguageEnglish
Published Singapore 2021
Subjects
Online AccessGet more information

Cover

Loading…
Abstract As a traditional Chinese alternative health care approach, acupuncture is gaining increasing attention and reputation in China and overseas. While becoming increasingly popular globally, some consumers and professionals still know little about the therapy and underlying mechanisms of acupuncture. Due to local superiority, there are large numbers of both clinical applications and mechanistic studies performed in China compared to countries overseas. Herein, this review attempts to give a comprehensive profile of the development, application, and mechanisms of acupuncture in treating major diseases. The number of clinical publications concerning acupuncture-treated neurological diseases, endocrine and metabolic diseases, circulatory diseases, respiratory diseases, etc. is first counted, and then, the application and therapeutic mechanisms of acupuncture on the predominant diseases in each category, including obesity, facial paralysis, sciatica, depression, hypertension, asthma, etc., are specifically discussed in this paper. The evolution of acupuncture tools and the rationality of acupoints are also discussed. This review not only summarizes the mechanisms of acupuncture but also provides useful information, such as specific acupoints and acupuncture procedures, for treating common diseases. Therefore, the current study provides useful information for both investigators and acupuncturists.
AbstractList As a traditional Chinese alternative health care approach, acupuncture is gaining increasing attention and reputation in China and overseas. While becoming increasingly popular globally, some consumers and professionals still know little about the therapy and underlying mechanisms of acupuncture. Due to local superiority, there are large numbers of both clinical applications and mechanistic studies performed in China compared to countries overseas. Herein, this review attempts to give a comprehensive profile of the development, application, and mechanisms of acupuncture in treating major diseases. The number of clinical publications concerning acupuncture-treated neurological diseases, endocrine and metabolic diseases, circulatory diseases, respiratory diseases, etc. is first counted, and then, the application and therapeutic mechanisms of acupuncture on the predominant diseases in each category, including obesity, facial paralysis, sciatica, depression, hypertension, asthma, etc., are specifically discussed in this paper. The evolution of acupuncture tools and the rationality of acupoints are also discussed. This review not only summarizes the mechanisms of acupuncture but also provides useful information, such as specific acupoints and acupuncture procedures, for treating common diseases. Therefore, the current study provides useful information for both investigators and acupuncturists.
Author Chen, Xi
Zhou, Ziwei
Wu, Weihua
He, Kai
Wen, Jingyi
Liu, Jiayou
Liu, Jianxin
Li, Enyin
Yang, Yong
Author_xml – sequence: 1
  givenname: Jingyi
  surname: Wen
  fullname: Wen, Jingyi
  organization: School of Pharmaceutical Science, Hunan University of Medicine, Huaihua 418000, P. R. China
– sequence: 2
  givenname: Xi
  surname: Chen
  fullname: Chen, Xi
  organization: School of Pharmaceutical Science, Hunan University of Medicine, Huaihua 418000, P. R. China
– sequence: 3
  givenname: Yong
  surname: Yang
  fullname: Yang, Yong
  organization: School of Pharmacy, Hunan University of Traditional Chinese Medicine, Changsha 410208, P. R. China
– sequence: 4
  givenname: Jianxin
  surname: Liu
  fullname: Liu, Jianxin
  organization: School of Pharmaceutical Science, Hunan University of Medicine, Huaihua 418000, P. R. China
– sequence: 5
  givenname: Enyin
  surname: Li
  fullname: Li, Enyin
  organization: School of Pharmaceutical Science, Hunan University of Medicine, Huaihua 418000, P. R. China
– sequence: 6
  givenname: Jiayou
  surname: Liu
  fullname: Liu, Jiayou
  organization: School of Pharmaceutical Science, Hunan University of Medicine, Huaihua 418000, P. R. China
– sequence: 7
  givenname: Ziwei
  surname: Zhou
  fullname: Zhou, Ziwei
  organization: School of Pharmaceutical Science, Hunan University of Medicine, Huaihua 418000, P. R. China
– sequence: 8
  givenname: Weihua
  surname: Wu
  fullname: Wu, Weihua
  organization: Hunan Provincial Key Laboratory of Dong Medicine, Hunan University of Medicine, Huaihua 418000, P. R. China
– sequence: 9
  givenname: Kai
  surname: He
  fullname: He, Kai
  organization: Hunan Provincial Key Laboratory of Dong Medicine, Hunan University of Medicine, Huaihua 418000, P. R. China
BackLink https://www.ncbi.nlm.nih.gov/pubmed/33371816$$D View this record in MEDLINE/PubMed
BookMark eNo1j11LwzAYRoMo7kN_gDeSP1DNmzRJ410ZfsFUcBt4N7LkrYu0sTSt0n_vQL164HA48MzIcfyMSMgFsCuAnF-vGBieg3zjIBljkB-RKWgjMlVIMSGzlD4OVOhCnZKJEEJDAWpKnks3tEN0_dAhfUIfnK3peo-dbUdqo6ehT3QTPXb1GOL7QXF7G0Nq0g0t6WpMPTa2D46-4lfA7zNyUtk64fnfzsnm7na9eMiWL_ePi3KZOaF4n1WVV9YZaVCowjvGBAhXSdTKojSeM58LmwtdaalsYXcaUArGvQE0qqgsn5PL32477Br027YLje3G7f8x_gNxJVBo
CitedBy_id crossref_primary_10_1002_ca_24077
crossref_primary_10_2147_JPR_S401086
crossref_primary_10_1016_j_forsciint_2023_111619
crossref_primary_10_3389_fneur_2024_1441886
crossref_primary_10_3389_fmed_2023_1232127
crossref_primary_10_1016_j_medntd_2023_100207
crossref_primary_10_2174_1573405619666230217120343
crossref_primary_10_1371_journal_pone_0283375
crossref_primary_10_1039_D3NR06102G
crossref_primary_10_3389_fmed_2022_952159
crossref_primary_10_1177_1759720X241271775
crossref_primary_10_3389_fnbeh_2021_783056
crossref_primary_10_1097_MD_0000000000039652
crossref_primary_10_3389_fnbeh_2021_655214
crossref_primary_10_1007_s10103_024_03999_z
crossref_primary_10_3389_fendo_2023_1237260
crossref_primary_10_62347_MJPK6664
crossref_primary_10_3389_fcimb_2024_1371543
crossref_primary_10_1007_s11916_023_01120_7
crossref_primary_10_1186_s13020_024_00916_y
crossref_primary_10_2147_JPR_S471441
crossref_primary_10_1002_jbio_202300124
crossref_primary_10_2196_55996
crossref_primary_10_1016_j_eujim_2022_102150
crossref_primary_10_1016_j_joim_2024_08_004
crossref_primary_10_3389_fimmu_2023_1147718
crossref_primary_10_5993_AJHB_48_5_8
crossref_primary_10_1016_j_heliyon_2023_e22422
crossref_primary_10_3389_fneur_2024_1368988
crossref_primary_10_3389_fneur_2024_1402458
crossref_primary_10_1142_S0192415X21500750
crossref_primary_10_62347_VYKU6210
crossref_primary_10_1097_MD_0000000000038898
crossref_primary_10_1016_j_jpha_2022_12_004
crossref_primary_10_1016_j_canlet_2024_217094
crossref_primary_10_1016_j_hipert_2023_11_001
crossref_primary_10_3389_fmed_2025_1525639
crossref_primary_10_3389_fneur_2023_1248348
crossref_primary_10_2147_JIR_S404087
crossref_primary_10_1155_2023_8510213
crossref_primary_10_1007_s00520_023_07967_1
crossref_primary_10_3389_fendo_2022_1009537
crossref_primary_10_3389_fnins_2023_1297149
crossref_primary_10_1016_j_neuropsychologia_2023_108669
crossref_primary_10_1097_CM9_0000000000002314
crossref_primary_10_1016_j_cvsm_2023_02_016
crossref_primary_10_3389_fnins_2024_1443834
crossref_primary_10_1093_qjmed_hcad134
crossref_primary_10_1016_j_imr_2025_101121
crossref_primary_10_1186_s12903_023_03806_1
crossref_primary_10_2147_IJGM_S356666
crossref_primary_10_1016_j_joim_2022_05_002
crossref_primary_10_1016_j_lfs_2023_122031
crossref_primary_10_3389_fpsyt_2022_1087706
crossref_primary_10_1002_mog2_73
crossref_primary_10_1097_MD_0000000000028047
crossref_primary_10_1186_s13098_024_01489_4
crossref_primary_10_62347_KFNE8547
crossref_primary_10_13066_kspm_2023_18_1_1
crossref_primary_10_1007_s10815_023_02898_6
crossref_primary_10_1016_j_gerinurse_2022_04_022
crossref_primary_10_3389_fneur_2022_931412
crossref_primary_10_3389_fneur_2022_956931
crossref_primary_10_1007_s11064_023_03970_4
crossref_primary_10_1515_tnsci_2022_0316
crossref_primary_10_1002_adbi_202400172
crossref_primary_10_1136_bmjopen_2023_081059
crossref_primary_10_1016_j_jstrokecerebrovasdis_2023_107524
crossref_primary_10_1016_j_ctim_2025_103162
crossref_primary_10_1016_j_dcmed_2024_01_001
crossref_primary_10_1097_MD_0000000000038314
crossref_primary_10_1016_j_jtcme_2024_03_014
crossref_primary_10_1016_j_jtos_2023_04_011
crossref_primary_10_3390_curroncol30070500
crossref_primary_10_1016_j_ctim_2023_102997
crossref_primary_10_3389_fnins_2025_1489049
crossref_primary_10_1016_j_ctcp_2022_101677
ContentType Journal Article
DBID NPM
DOI 10.1142/S0192415X21500014
DatabaseName PubMed
DatabaseTitle PubMed
DatabaseTitleList PubMed
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
DeliveryMethod no_fulltext_linktorsrc
Discipline Medicine
EISSN 1793-6853
ExternalDocumentID 33371816
Genre Journal Article
GroupedDBID ---
.GJ
0R~
123
23M
36B
4.4
53G
5RE
6J9
6NX
6PF
AAWTL
ADSJI
AEGXH
AENEX
AFOSN
AIZAD
ALMA_UNASSIGNED_HOLDINGS
C1A
CAG
COF
CS3
EBS
ECV
EJD
EMOBN
ESX
F5P
FAL
FEDTE
FJD
FJW
HVGLF
HZ~
NPM
O9-
P2P
P71
PQQKQ
RWJ
WH7
WQ9
WSL
ZGI
ZXP
ID FETCH-LOGICAL-c362t-ffd6ac959e368dc00313cf5e76ae59d20d43a437f756a8ab71e5302d91e968fa2
IngestDate Thu Jan 02 22:57:17 EST 2025
IsPeerReviewed true
IsScholarly true
Issue 1
Keywords Therapy
Disease
Electroacupuncture
Acupuncture
Review
Mechanism
Acupoints
Language English
LinkModel OpenURL
MergedId FETCHMERGED-LOGICAL-c362t-ffd6ac959e368dc00313cf5e76ae59d20d43a437f756a8ab71e5302d91e968fa2
PMID 33371816
ParticipantIDs pubmed_primary_33371816
PublicationCentury 2000
PublicationDate 2021-00-00
PublicationDateYYYYMMDD 2021-01-01
PublicationDate_xml – year: 2021
  text: 2021-00-00
PublicationDecade 2020
PublicationPlace Singapore
PublicationPlace_xml – name: Singapore
PublicationTitle The American journal of Chinese medicine (1979)
PublicationTitleAlternate Am J Chin Med
PublicationYear 2021
SSID ssj0013786
Score 2.540177
Snippet As a traditional Chinese alternative health care approach, acupuncture is gaining increasing attention and reputation in China and overseas. While becoming...
SourceID pubmed
SourceType Index Database
StartPage 1
Title Acupuncture Medical Therapy and its Underlying Mechanisms: A Systematic Review
URI https://www.ncbi.nlm.nih.gov/pubmed/33371816
Volume 49
hasFullText
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1bS8MwFA6bwvBFvN8lD75Wl7ZJWt-GKEPYXtxwexppk8LEXWAbqE_-dE-T9OKcor6UkTRrm_Plcs7J-Q5CFzGMgsCNiEMTCQoKqGtOIAh1JJO-jDhVQgcKt9qs2fXve7RXqbyXTi0t5tFl_LYyruQ_UoUykGsaJfsHyeZ_CgXwG-QLV5AwXH8l40a8mMK6pJ0AmcelY2gCcqeATmz0rIOZWioN8x3ORjMTj_5QsDiXXARPBX5yd06JXyJNuK1mKnfKa6ankIclk8KjDfiAZ74Oi_MDprSXl_Stqbo_satnei5ouDBNxfjFcoJbk4RLSiYJZaZRGPUOCwwNcDbPGmrST3gykyZZPZX7rnYmpxoiAZWaUK3Ple-FzpqOtGw9z4NF1kRt_ly7xK6dVVVRFfSMNHFqau3JvFA8YNYTDm9z9eVdNlAta7-klejdSWcLbVq1AjcMRrZRRY13UK1lZbSL2iWoYAsVbKGCASoYoIILqOACKte4gQugYAOUPdS9u-3cNB2bSsOJYYcyd5JEMhGHNFQeC2SsGTvjhCrOhKKhdOvS94Tv8YRTJgIRcaLSdFIyJCpkQSLcfbQ2nozVIcLwwcKvxxGPNDETTPgCWlLPhaWTuIofoQPTE4Op4UsZZH10_G3NCdoocHSK1hMYoOoMdnvz6FyL5APdrlEQ
linkProvider National Library of Medicine
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Acupuncture+Medical+Therapy+and+its+Underlying+Mechanisms%3A+A+Systematic+Review&rft.jtitle=The+American+journal+of+Chinese+medicine+%281979%29&rft.au=Wen%2C+Jingyi&rft.au=Chen%2C+Xi&rft.au=Yang%2C+Yong&rft.au=Liu%2C+Jianxin&rft.date=2021-01-01&rft.eissn=1793-6853&rft.volume=49&rft.issue=1&rft.spage=1&rft_id=info:doi/10.1142%2FS0192415X21500014&rft_id=info%3Apmid%2F33371816&rft_id=info%3Apmid%2F33371816&rft.externalDocID=33371816