Repeater F-waves in amyotrophic lateral sclerosis: Electrophysiologic indicators of upper or lower motor neuron involvement?

• Published in: Clinical neurophysiology Vol. 131; no. 1; pp. 96 - 105
• Main Authors: Oguz Akarsu, Emel, Sirin, Nermin Gorkem, Kocasoy Orhan, Elif, Erbas, Bahar, Dede, Hava Ozlem, Baslo, Mehmet Baris, Idrisoglu, Halil Atilla, Oge, Ali Emre
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.01.2020
• Subjects: Amyotrophic lateral sclerosis; Amyotrophic Lateral Sclerosis - physiopathology; Case-Control Studies; Electrophysiological Phenomena; Evoked Potentials - physiology; Female; Humans; Male; Median Nerve - physiopathology; Middle Aged; Motor Neurons - physiology; MScanFit MUNE; Muscle, Skeletal - innervation; Neural Conduction - physiology; Neurophysiological Monitoring; Repeater F-wave; Split hand; Transcranial magnetic stimulation; Transcranial Magnetic Stimulation - methods; Triple stimulation technique; Ulnar Nerve - physiopathology; MScanFit MUNE; Triple stimulation technique; Amyotrophic lateral sclerosis; Repeater F-wave; Transcranial magnetic stimulation; Split hand

•Repeater F-waves (Frep) seem to be related to lower motor neuron loss in ALS.•None of the transcranial magnetic stimulation measures was correlated with Frep in ALS.•Lower F-wave persistence in APB muscle may predict the subsequent split hand phenomenon. To extract insight about the mechanism of re...