Dimetallic Ru(II) arene complexes appended on bis-salicylaldimine induce cancer cell death and suppress invasion via p53-dependent signaling - Rahman, Faiz-Ur; Bhatti, Muhammad Zeeshan; Ali, Amjad; Duong, Hong-Quan; Zhang, Yao; Ji, Xinjian; Lin, Yuejian; Wang, Hui; Li, Zhan-Ting; Zhang, Dan-Wei (European journal of medicinal chemistry, 2018)
Keywords: Antineoplastic Agents - chemical synthesis; Antineoplastic Agents - chemistry; Antineoplastic Agents - pharmacology; bis-Salicylaldimine; Cell Death - drug effects; Cell Line, Tumor; Cell Movement - drug effects; Cell Proliferation - drug effects; Chemistry, Medicinal; Dimetallic complexes; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Life Sciences & Biomedicine; Molecular Structure; Neoplasm Invasiveness - pathology; Neoplasm Invasiveness - prevention & control; Organometallic Compounds - chemical synthesis; Organometallic Compounds - chemistry; Organometallic Compounds - pharmacology; Pharmacology & Pharmacy; Ru(II) anticancer complexes; Ru-(p-cymene); Ru-anticancer complexes; Ruthenium - chemistry; Ruthenium - pharmacology; Science & Technology; Signal Transduction - drug effects; Structure-Activity Relationship; Tumor Suppressor Protein p53 - metabolism; Ru(II) anticancer complexes; Dimetallic complexes; bis-Salicylaldimine; Ru-anticancer complexes; Ru-(p-cymene); ANTIPROLIFERATIVE ACTIVITY; COPPER-COMPLEXES; PHOTODYNAMIC THERAPY; ESCHERICHIA-COLI; CISPLATIN RESISTANCE; IN-VITRO CYTOTOXICITY; ORGANOMETALLIC ANTICANCER COMPLEXES; LIGANDS SYNTHESIS; RUTHENIUM COMPLEXES; MOLECULAR-MECHANISMS