The relevance of DHA with modulating of host-gut microbiome signatures alterations and repairing of lipids metabolism shifts

• Published in: European journal of pharmacology Vol. 895; p. 173885
• Main Authors: Yu, Haining, Fang, Chengjie, Li, Peng, Wu, Manman, Shen, Shengrong
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 15.03.2021
• Subjects: Animals; Anti-Bacterial Agents - toxicity; Bacteria - drug effects; Bacteria - growth & development; Bacteria - metabolism; Bile acids; Bile Acids and Salts - metabolism; Biomarkers - blood; DHA; Docosahexaenoic Acids - metabolism; Docosahexaenoic Acids - pharmacology; Dysbiosis; Fatty acids; Fatty Acids - blood; Feces - chemistry; Female; Gastrointestinal Microbiome - drug effects; Gut microbiome; High-Throughput Screening Assays; Intestines - microbiology; Lipid Metabolism - drug effects; Lipidomics; Lipids metabolism; Liver - drug effects; Liver - metabolism; Male; Metabolome - drug effects; Mice; Mice, Inbred BALB C; Lipids metabolism; Bile acids; DHA; Gut microbiome; Fatty acids

Huge of previous reports recommended that gut microbiome have a crucial role in the human health and its change was profound impact for the metabolic improvements associated with lipids metabolism. In order to explore the relevance of a direct dysbiosis effect of gut microbiome on lipids metabolism...