Quantitative biochemical characterization and biotechnological production of caspase modulator, XIAP: Therapeutic implications for apoptosis-associated diseases - Yun, Si-Eun; Nam, Min-Kyung; Rhim, Hyangshuk (Biochimica et biophysica acta, 2018)
Keywords: Apoptosis; Apoptosis - drug effects; BIR2 domain; BIR3 domain; Caspase3 inhibition; Caspases - metabolism; Drug Evaluation, Preclinical; Enzyme Activation - drug effects; HEK293 Cells; High-Temperature Requirement A Serine Peptidase 2 - metabolism; HtrA2 binding affinity; Humans; Neoplasms - drug therapy; Neurodegenerative Diseases - drug therapy; Protein Binding; Protein Domains; Recombinant Fusion Proteins - metabolism; X-Linked Inhibitor of Apoptosis Protein - analysis; X-Linked Inhibitor of Apoptosis Protein - genetics; X-Linked Inhibitor of Apoptosis Protein - isolation & purification; X-Linked Inhibitor of Apoptosis Protein - pharmacology; XIAP; Caspase3 inhibition; HtrA2 binding affinity; XIAP; BIR2 domain; BIR3 domain; Apoptosis