Dependence of cortical neuronal strength-duration properties on TMS pulse shape

• Published in: Clinical neurophysiology Vol. 150; pp. 106 - 118
• Main Authors: Menon, Parvathi, Pavey, Nathan, Aberra, Aman S., van den Bos, Mehdi A.J., Wang, Ruochen, Kiernan, Matthew C., Peterchev, Angel V., Vucic, Steve
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.06.2023
• Subjects: Axons; cTMS; Evoked Potentials, Motor - physiology; Heart Rate; Humans; Neurons; Rheobase; SDTC; Sodium channel; Strength-duration time constant; Transcranial Magnetic Stimulation - methods; cTMS; Sodium channel; Strength-duration time constant; Rheobase; SDTC

•The TMS pulse shape and selection of pulse widths influences the properties of the cortical strength-duration curve.•Larger hyperpolarizing TMS pulse trailing phase increases motor thresholds resulting in longer cortical strength-duration time constant and smaller rheobase.•Modulation of transient...