Genetic conservation of Cytauxzoon felis antigens and mRNA expression in the schizont life-stage

• Published in: Veterinary parasitology Vol. 263; pp. 49 - 53
• Main Authors: Khana, Daven B., Peterson, David S., Stanton, James B., Schreeg, Megan E., Birkenheuer, Adam J., Tarigo, Jaime L.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 15.11.2018
• Subjects: Animals; Antigen; Antigens, Protozoan - genetics; Cat Diseases - parasitology; Cats; Cytauxzoon felis; Cytauxzoonosis; DNA, Protozoan - genetics; Feline; Genetic conservation; Piroplasmida - genetics; Protozoan Infections, Animal - mortality; Protozoan Infections, Animal - parasitology; Protozoan Infections, Animal - prevention & control; Protozoan Vaccines - genetics; Protozoan Vaccines - immunology; RNA, Messenger - genetics; Schizonts - genetics; Vaccine candidate; Antigen; Vaccine candidate; Cytauxzoonosis; Feline; Cytauxzoon felis; Genetic conservation

•Nucleotide and amino acid sequence conservation is 99–100% amongst vaccine candidates.•The vaccine candidates were predicted to have one or more transmembrane helices.•The vaccine candidates were predicted to have no signal peptide cleavage sites.•The vaccine candidates are robustly expressed in th...