Noncoding translation: Quality control in the BAG
Translation of noncoding regions is ubiquitous and upregulated in disease. Kesner et al.1 elucidate the mechanism by which the BAG6 complex exerts quality control over noncoding translation while targeting stable, noncanonical polypeptides to cellular membranes. Translation of noncoding regions is u...
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Published in | Molecular cell Vol. 83; no. 12; pp. 1967 - 1969 |
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Format | Journal Article |
Language | English |
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Elsevier Inc
15.06.2023
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Abstract | Translation of noncoding regions is ubiquitous and upregulated in disease. Kesner et al.1 elucidate the mechanism by which the BAG6 complex exerts quality control over noncoding translation while targeting stable, noncanonical polypeptides to cellular membranes.
Translation of noncoding regions is ubiquitous and upregulated in disease. Kesner et al.1 elucidate the mechanism by which the BAG6 complex exerts quality control over noncoding translation while targeting stable, noncanonical polypeptides to cellular membranes. |
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AbstractList | Translation of noncoding regions is ubiquitous and upregulated in disease. Kesner et al.1 elucidate the mechanism by which the BAG6 complex exerts quality control over noncoding translation while targeting stable, noncanonical polypeptides to cellular membranes.Translation of noncoding regions is ubiquitous and upregulated in disease. Kesner et al.1 elucidate the mechanism by which the BAG6 complex exerts quality control over noncoding translation while targeting stable, noncanonical polypeptides to cellular membranes. Translation of noncoding regions is ubiquitous and upregulated in disease. Kesner et al. elucidate the mechanism by which the BAG6 complex exerts quality control over noncoding translation while targeting stable, noncanonical polypeptides to cellular membranes. Translation of noncoding regions is ubiquitous and upregulated in disease. Kesner et al.1 elucidate the mechanism by which the BAG6 complex exerts quality control over noncoding translation while targeting stable, noncanonical polypeptides to cellular membranes. Translation of noncoding regions is ubiquitous and upregulated in disease. Kesner et al.1 elucidate the mechanism by which the BAG6 complex exerts quality control over noncoding translation while targeting stable, noncanonical polypeptides to cellular membranes. |
Author | Mohsen, Jessica J. Slavoff, Sarah A. |
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BackLink | https://www.ncbi.nlm.nih.gov/pubmed/37327774$$D View this record in MEDLINE/PubMed |
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Cites_doi | 10.1038/nature11184 10.1038/s41589-019-0425-0 10.1016/j.molcel.2022.06.035 10.1038/s41587-021-01021-3 10.1038/s41587-020-00806-2 10.1038/s41586-023-05946-4 10.1126/science.aay0262 10.1126/science.1168978 10.1126/science.1238802 10.1038/s41467-020-14500-z |
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