Genetic association analysis of ATG16L1 rs2241880, rs6758317 and ATG16L2 rs11235604 polymorphisms with rheumatoid arthritis in a Chinese population

• Published in: International immunopharmacology Vol. 93; p. 107378
• Main Authors: Mo, Ji-Jun, Zhang, Wei, Wen, Qin-Wen, Wang, Ting-Hui, Qin, Wen, Zhang, Zhen, Huang, Hua, Cen, Han, Wu, Xiu-Di
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.04.2021
• Subjects: Adult; Aged; Arthritis, Rheumatoid - genetics; Asians - genetics; ATG16L1; ATG16L2; Autophagy; Autophagy-Related Proteins - genetics; Female; Genotype; Humans; Male; Middle Aged; Polymorphism; Polymorphism, Single Nucleotide; Rheumatoid arthritis; ATG16L2; ATG16L1; Autophagy; Rheumatoid arthritis; Polymorphism

•The ATG16L1 rs2241880 was associated with RA, CCP-positive RA and RF-positive RA.•Interaction between rs2241880 and rs11235604 was associated with RA.•Interaction between rs6758317 and rs11235604 was associated with RA, CCP-positive RA and RF-positive RA. This study was performed to test whether AT...