Computational model of cardiovascular response to centrifugation and lower body cycling exercise

• Published in: Journal of applied physiology (1985) Vol. 127; no. 5; pp. 1453 - 1468
• Main Authors: Diaz-Artiles, Ana, Heldt, Thomas, Young, Laurence R.
• Format: Journal Article
• Language: English
• Published: United States 01.11.2019
• Subjects: mathematical model; orthostatic intolerance; short-radius centrifuge; lower body ergometer exercise; cardiovascular simulation

Short-radius centrifugation combined with exercise has been suggested as a potential countermeasure against spaceflight deconditioning. Both the long-term and acute physiological responses to such a combination are incompletely understood. We developed and validated a computational model to study th...