High-flow nasal cannula for acute exacerbation of chronic obstructive pulmonary disease: A systematic review and meta-analysis

• Published in: Heart & lung Vol. 50; no. 2; pp. 252 - 261
• Main Authors: Yang, Peng-Lei, Yu, Jiang-Quan, Chen, Han-Bing
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.03.2021
• Subjects: Cannula; Chronic obstructive pulmonary disease; Humans; Meta-analysis; Non-invasive ventilation; Noninvasive Ventilation; Observational Studies as Topic; Oxygen Inhalation Therapy; Oxygen therapy; Pulmonary Disease, Chronic Obstructive - complications; Pulmonary Disease, Chronic Obstructive - therapy; Respiratory Insufficiency - therapy; Chronic obstructive pulmonary disease; Oxygen therapy; Non-invasive ventilation; Meta-analysis

·This meta-analysis showed that HFNC may not increase the risk of intubation or mortality compared to NIV, HFNC may not exacerbate hypercapnia and acidosis in AECOPD patients with hypercapnia and mild acidosis and patients weaned from invasive ventilation.·Compared to COT, HFNC may also not exacerba...