Use of counter-current chromatography as a selective extractor for the diterpenequinone 7α-hydroxyroyleanone from Tetradenia riparia

• Published in: Journal of Chromatography A Vol. 1537; pp. 135 - 140
• Main Authors: Milato, Jonatas Vicente, Silva, Raphael Salles Ferreira, Figueiredo, Fabiana de Souza, Azevedo, Debora de Almeida, Ribeiro, Carlos Alexandre Bulchi, Leitão, Gilda Guimarães
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 16.02.2018
• Subjects: 7α-hydroxyroyleanone; Counter-current chromatography; Horminone; Liquid-liquid extraction; Method validation; Tetradenia riparia; Liquid-liquid extraction; 7α-hydroxyroyleanone; Method validation; Horminone; Counter-current chromatography; Tetradenia riparia

•A method was developed for the selective isolation of 7α-hydroxyroyleanone, 1, from T. riparia.•The diterpene was first quantified in the extract by gas chromatography/mass spectrometry.•Five solvent systems for the purification of 1 by HSCCC were tested.•A new solvent system hexane −5% aq. Na2CO3...