Discovery of new benzensulfonamide derivatives as tripedal STAT3 inhibitors - Guo, Jianpeng; Yu, Wenying; Cai, Guiping; Zhang, Wenda; Li, Shanshan; Zhu, Jiawen; Song, Dongmei; Kong, Lingyi (European journal of medicinal chemistry, 2018)
Keywords: Antitumor activity; Apoptosis; Chemistry, Medicinal; Life Sciences & Biomedicine; Pharmacology & Pharmacy; Science & Technology; Selectivity; STAT3 phosphorylation; Structure-based drug design; Sulfonamide; rt; Sulfonamide; Structure-based drug design; DMSO; Selectivity; MTT; STAT; STAT3 phosphorylation; ROS; Antitumor activity; PI; TMS; SH2; GAPDH; Apoptosis; Erk; SMALL-MOLECULE; PHOSPHORYLATION; CANCER; BREAST; ACTIVATOR; THERAPY; SIGNAL TRANSDUCER; HYBRIDS