Double-Peak Response in Orthodromic Sensory Nerve Conduction of the Median Nerve
To understand the neural generator of double-peak potentials and the change of latency and amplitude of double peaks with aging. In 50 healthy subjects made up of groups of 10 people per decade from the age of 20 to 60, orthodromic sensory nerve conduction studies were performed on the median nerves...
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| Published in | Annals of rehabilitation medicine Vol. 35; no. 4; pp. 541 - 547 |
|---|---|
| Main Authors | , |
| Format | Journal Article |
| Language | English |
| Published |
Korea (South)
Korean Academy of Rehabilitation Medicine
01.08.2011
대한재활의학회 |
| Subjects | |
| Online Access | Get full text |
| ISSN | 2234-0645 2234-0653 2234-0653 |
| DOI | 10.5535/arm.2011.35.4.541 |
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| Abstract | To understand the neural generator of double-peak potentials and the change of latency and amplitude of double peaks with aging.
In 50 healthy subjects made up of groups of 10 people per decade from the age of 20 to 60, orthodromic sensory nerve conduction studies were performed on the median nerves using submaximal stimulation. Various stimulus durations and interstimulation distances were used to obtain each double peak in the different age groups. The latency and amplitude of the second peak were measured. Statistical analyses included one-way ANOVA and correlation tests. p-values<0.05 were considered significant.
When the cathode moved in a proximal direction, the interpeak intervals increased. Second peak amplitudes decreased, and second peak latencies were delayed with aging (p<0.05). In some older people, second peaks were not obtained.
Our experiments indicate that the double-peak response represented the two stimulation sites under the cathode and anode. The delayed latency and decreased amplitude of the second peak that occurs with aging represented peripheral nerve degeneration in aging, which starts at the distal nerve. |
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| AbstractList | To understand the neural generator of double-peak potentials and the change of latency and amplitude of double peaks with aging.
In 50 healthy subjects made up of groups of 10 people per decade from the age of 20 to 60, orthodromic sensory nerve conduction studies were performed on the median nerves using submaximal stimulation. Various stimulus durations and interstimulation distances were used to obtain each double peak in the different age groups. The latency and amplitude of the second peak were measured. Statistical analyses included one-way ANOVA and correlation tests. p-values<0.05 were considered significant.
When the cathode moved in a proximal direction, the interpeak intervals increased. Second peak amplitudes decreased, and second peak latencies were delayed with aging (p<0.05). In some older people, second peaks were not obtained.
Our experiments indicate that the double-peak response represented the two stimulation sites under the cathode and anode. The delayed latency and decreased amplitude of the second peak that occurs with aging represented peripheral nerve degeneration in aging, which starts at the distal nerve. To understand the neural generator of double-peak potentials and the change of latency and amplitude of double peaks with aging.OBJECTIVETo understand the neural generator of double-peak potentials and the change of latency and amplitude of double peaks with aging.In 50 healthy subjects made up of groups of 10 people per decade from the age of 20 to 60, orthodromic sensory nerve conduction studies were performed on the median nerves using submaximal stimulation. Various stimulus durations and interstimulation distances were used to obtain each double peak in the different age groups. The latency and amplitude of the second peak were measured. Statistical analyses included one-way ANOVA and correlation tests. p-values<0.05 were considered significant.METHODIn 50 healthy subjects made up of groups of 10 people per decade from the age of 20 to 60, orthodromic sensory nerve conduction studies were performed on the median nerves using submaximal stimulation. Various stimulus durations and interstimulation distances were used to obtain each double peak in the different age groups. The latency and amplitude of the second peak were measured. Statistical analyses included one-way ANOVA and correlation tests. p-values<0.05 were considered significant.When the cathode moved in a proximal direction, the interpeak intervals increased. Second peak amplitudes decreased, and second peak latencies were delayed with aging (p<0.05). In some older people, second peaks were not obtained.RESULTSWhen the cathode moved in a proximal direction, the interpeak intervals increased. Second peak amplitudes decreased, and second peak latencies were delayed with aging (p<0.05). In some older people, second peaks were not obtained.Our experiments indicate that the double-peak response represented the two stimulation sites under the cathode and anode. The delayed latency and decreased amplitude of the second peak that occurs with aging represented peripheral nerve degeneration in aging, which starts at the distal nerve.CONCLUSIONOur experiments indicate that the double-peak response represented the two stimulation sites under the cathode and anode. The delayed latency and decreased amplitude of the second peak that occurs with aging represented peripheral nerve degeneration in aging, which starts at the distal nerve. Objective To understand the neural generator of double-peak potentials and the change of latency and amplitude of double peaks with aging. Method In 50 healthy subjects made up of groups of 10 people per decade from the age of 20 to 60, orthodromic sensory nerve conduction studies were performed on the median nerves using submaximal stimulation. Various stimulus durations and interstimulation distances were used to obtain each double peak in the different age groups. The latency and amplitude of the second peak were measured. Statistical analyses included one-way ANOVA and correlation tests. p-values<0.05 were considered significant. Results When the cathode moved in a proximal direction, the interpeak intervals increased. Second peak amplitudes decreased, and second peak latencies were delayed with aging (p<0.05). In some older people, second peaks were not obtained. Conclusion Our experiments indicate that the double-peak response represented the two stimulation sites under the cathode and anode. The delayed latency and decreased amplitude of the second peak that occurs with aging represented peripheral nerve degeneration in aging, which starts at the distal nerve. KCI Citation Count: 0 |
| Author | Joa, Kyung Lim Kim, Chang-Hwan |
| AuthorAffiliation | 1 Department of Physical & Rehabilitation Medicine, School of Medicine, Inha University, Incheon 400-711, Korea 2 Department of Physical & Rehabilitation Medicine, Pusan National University School of Medicine, Yangsan 626-770, Korea |
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| Keywords | Nerve conduction study Aging Nerve degeneration Double peak response |
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| Snippet | To understand the neural generator of double-peak potentials and the change of latency and amplitude of double peaks with aging.
In 50 healthy subjects made up... To understand the neural generator of double-peak potentials and the change of latency and amplitude of double peaks with aging.OBJECTIVETo understand the... Objective To understand the neural generator of double-peak potentials and the change of latency and amplitude of double peaks with aging. Method In 50 healthy... |
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| Title | Double-Peak Response in Orthodromic Sensory Nerve Conduction of the Median Nerve |
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