Polymorphisms in the nuclear factor kappa B gene association with recurrent embryo implantation failure

• Published in: Genetics and molecular research Vol. 15; no. 2
• Main Authors: Luo, L., Li, D.H., Li, X.P., Zhang, S.C., Yan, C.F., Wu, J.F., Qi, Y.H., Zhao, J.
• Format: Journal Article
• Language: English
• Published: Brazil 01.01.2016
• Subjects: Adult; Case-Control Studies; Embryo Implantation - genetics; Embryo Transfer - adverse effects; Female; Haplotypes; Humans; Linkage Disequilibrium; NF-kappa B - genetics; Polymorphism, Single Nucleotide; Pregnancy

Despite more than a century of intensive study, the mechanisms of successful pregnancy remain unclear. Recent research suggests that NF-κB (nuclear factor kappa B) plays an important role in embryo implantation. In the current study, we aimed to identify SNPs that contribute to genetic susceptibilit...