Newer anti-epileptic drugs, vitamin status and neuropathy: A cross-sectional analysis

• Published in: Revue neurologique Vol. 173; no. 1-2; pp. 62 - 66
• Main Authors: Cahill, V., McCorry, D., Soryal, I., Rajabally, Y.A.
• Format: Journal Article
• Language: English
• Published: France Elsevier Masson SAS 01.01.2017
• Subjects: Adult; Anti-epileptic drugs; Anticonvulsants - therapeutic use; Cross-Sectional Studies; Drugs, Investigational - therapeutic use; Epilepsy; Epilepsy - blood; Epilepsy - complications; Epilepsy - drug therapy; Exposure; Female; Folate; Folic Acid - blood; Humans; Male; Middle Aged; Neuropathy; Nutritional Status; Peripheral Nervous System Diseases - blood; Peripheral Nervous System Diseases - complications; Peripheral Nervous System Diseases - drug therapy; Vitamin B 12 - blood; Vitamin B12; Vitamins - blood; Young Adult; Anti-epileptic drugs; Exposure; Neuropathy; Vitamin B12; Epilepsy; Folate

Whether new antiepileptic drugs (AEDs) may result in neuropathy is unknown but possible given their effects on vitamin metabolism. This analysis aimed to determine frequency and correlates of neuropathy in subjects treated with new AEDs in relation to drug used, length of exposure and serum vitamin...