Experimental evidence for curcumin and its analogs for management of diabetes mellitus and its associated complications

• Published in: European journal of pharmacology Vol. 756; pp. 30 - 37
• Main Authors: Rivera-Mancía, Susana, Lozada-García, María Concepción, Pedraza-Chaverri, José
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 05.06.2015
• Subjects: Animals; Blood Glucose - metabolism; Curcumin - analogs & derivatives; Curcumin - pharmacology; Curcumin - therapeutic use; Curcumin analogs; Diabetes Complications - blood; Diabetes Complications - drug therapy; Diabetes mellitus; Diabetes Mellitus - blood; Diabetes Mellitus - drug therapy; Diabetic cardiomyopathy; Diabetic nephropathy; Humans; Hypoglycemic Agents - chemistry; Hypoglycemic Agents - pharmacology; Hypoglycemic Agents - therapeutic use; Diabetic cardiomyopathy; Diabetic nephropathy; Diabetes mellitus; Curcumin analogs

Diabetes mellitus is a serious world health problem and one of the most studied diseases; a major concern about its treatment is that β-cell mass and functionality is hard to restore. In addition, it is frequently associated with severe complications, such as diabetic nephropathy and cardiomyopathy....