Single-cell coating with biomimetic extracellular nanofiber matrices

• Published in: Acta biomaterialia Vol. 177; pp. 50 - 61
• Main Authors: Lee, Slgirim, Carrow, James K., Fraser, Lewis A., Yan, Jianglong, Jeyamogan, Shareni, Sambandam, Yuvaraj, Clemons, Tristan D., Kolberg-Edelbrock, Alexandra N., He, Jie, Mathew, James, Zhang, Zheng Jenny, Leventhal, Joseph P., Gallon, Lorenzo, Palmer, Liam C., Stupp, Samuel I.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 15.03.2024
• Subjects: Artificial extracellular matrices; Peptide amphiphiles; Regenerative medicine; Regulatory T cells; Single cell coating; Supramolecular scaffolds; Peptide amphiphiles; Supramolecular scaffolds; Regulatory T cells; Regenerative medicine; Artificial extracellular matrices; Single cell coating

Cell therapies offer great promise in the treatment of diseases and tissue regeneration, but their clinical use has many challenges including survival, optimal performance in their intended function, or localization at sites where they are needed for effective outcomes. We report here on a method to...