Subclinical Hypothyroidism in HIV-Infected Patients Is Not an Autoimmune Disease

• Published in: Hormone research Vol. 66; no. 1; pp. 21 - 26
• Main Authors: Beltran, S., Lescure, F.-X., El Esper, I., Schmit, J.-L., Desailloud, R.
• Format: Journal Article
• Language: English
• Published: Basel, Switzerland S. Karger AG 01.01.2006
• Subjects: Adult; Antiretroviral Therapy, Highly Active; Autoantibodies - blood; Autoimmune Diseases; HIV Infections - complications; HIV Infections - drug therapy; HIV Infections - immunology; Human immunodeficiency virus; Humans; Hypogonadism - complications; Hypogonadism - diagnosis; Hypothyroidism - complications; Hypothyroidism - diagnosis; Interferon-gamma - blood; Iodine - urine; Middle Aged; Original Paper; Prospective Studies; Thyroid Gland - diagnostic imaging; Thyroid Gland - immunology; Thyrotropin - blood; Thyrotropin-Releasing Hormone; Thyroxine - blood; Triiodothyronine - blood; Triiodothyronine, Reverse - blood; Ultrasonography; Antiretrovirals; Dialysis equilibrium; Hypothyroidism; HIV infection; Highly active anti-retroviral therapy

Aims and Methods: A study of 350 HIV+ patients in our region showed that 16% suffered from hypothyroidism. Twenty-two HIV+ hypothyroid patients (10 with subclinical hypothyroidism, 12 with low FT4 levels (LT4) (confirmed by a dialysis equilibrium assay) and 22 HIV+ euthyroid controls receiving highl...