Combined exercise hinders the progression of pulmonary and right heart harmful remodeling in monocrotaline-induced pulmonary arterial hypertension - Leite, Luciano Bernardes; Soares, Leôncio Lopes; Portes, Alexandre Martins Oliveira; da Silva, Bruna Aparecida Fonseca; Dias, Taís Rodrigues; Soares, Thayana Inácia; Assis, Mirian Quintão; Guimarães-Ervilha, Luiz Otávio; Carneiro-Júnior, Miguel Araújo; Forte, Pedro; Machado-Neves, Mariana; Reis, Emily Correna Carlo; et al. (Journal of applied physiology (1985), 2025)
Keywords: Acceleration; Alveoli; Amplitudes; Animals; Calcium (intracellular); Calcium ions; Carbonyl compounds; Carbonyls; Cardiomyocytes; Catalase; Disease Progression; Exercise; Extracellular matrix; Fitness training programs; Glutathione; Glutathione transferase; Heart; Heart Ventricles - metabolism; Heart Ventricles - physiopathology; Hypertension; Hypertension, Pulmonary - chemically induced; Hypertension, Pulmonary - metabolism; Hypertension, Pulmonary - physiopathology; Load resistance; Lung - metabolism; Lung - physiopathology; Lungs; Male; Monocrotaline; Myocytes; Myocytes, Cardiac - metabolism; Myocytes, Cardiac - pathology; Nitric oxide; Oxidative stress; Oxidative Stress - physiology; Physical Conditioning, Animal - physiology; Physical exercise; Physical training; Physiology; Pulmonary Arterial Hypertension - chemically induced; Pulmonary Arterial Hypertension - metabolism; Pulmonary Arterial Hypertension - physiopathology; Pulmonary arteries; Pulmonary artery; Pulmonary Artery - metabolism; Pulmonary Artery - physiopathology; Pulmonary hypertension; Rats; Rats, Wistar; Running; Structure-function relationships; Ventricular Function, Right - physiology; Ventricular Remodeling - physiology; Vertical loads; combined exercise training; remodeling; isolated myocytes; pulmonary arterial hypertension; oxidative stress