Functional proteasome complex is required for turnover of islet amyloid polypeptide in pancreatic β-cells - Chatterjee Bhowmick, Diti; Jeremic, Aleksandar (The Journal of biological chemistry, 2018)
Keywords: Acetylcysteine - analogs & derivatives; Acetylcysteine - pharmacology; Animals; Cell Line, Tumor; Diabetes Mellitus, Type 2 - metabolism; Diabetes Mellitus, Type 2 - pathology; Down-Regulation; Hepatocyte Nuclear Factor 3-beta - metabolism; Humans; Insulin-Secreting Cells - enzymology; Insulin-Secreting Cells - metabolism; Insulinoma - enzymology; Insulinoma - metabolism; Islet Amyloid Polypeptide - genetics; Islet Amyloid Polypeptide - metabolism; Leupeptins - pharmacology; Mice; Oligopeptides - pharmacology; Promoter Regions, Genetic; Proteasome Endopeptidase Complex - drug effects; Proteasome Endopeptidase Complex - metabolism; Proteasome Inhibitors - pharmacology; Protein Synthesis and Degradation; Rats; hyperglycemia; proteasome; amyloid; secretion; type 2 diabetes; insulin; transcription; Islet amyloid polypeptide; FoxA2