Residential exposure to Aspergillus spp . is associated with exacerbations in COPD

• Published in: The European respiratory journal Vol. 64; no. 5; p. 2400907
• Main Authors: Tiew, Pei Yee, Leung, Janice M., Mac Aogáin, Micheál, Johal, Parteek, Jaggi, Tavleen Kaur, Yuen, Agnes Che Yan, Ivan, Fransiskus Xaverius, Yang, Julia, Afshar, Tina, Tee, Augustine, Koh, Mariko Siyue, Lim, Yee Hui, Wong, Anthony, Chandrasekaran, Lakshmi, Dacanay, Justine G., Drautz-Moses, Daniela I., Ong, Thun How, Abisheganaden, John A., Chew, Fook Tim, Schuster, Stephan C., Carlsten, Christopher, Chotirmall, Sanjay H.
• Format: Journal Article
• Language: English
• Published: England European Respiratory Society 01.11.2024
• Subjects: Aged; Air Pollution, Indoor; Allergens - immunology; Aspergillus fumigatus - immunology; British Columbia - epidemiology; Disease Progression; Environmental Exposure; Female; Housing; Humans; Male; Metagenomics; Middle Aged; Original; Prospective Studies; Pulmonary Disease, Chronic Obstructive - immunology; Pulmonary Disease, Chronic Obstructive - microbiology; Singapore - epidemiology; British Columbia; Singapore

Sensitisation to is linked to worse outcomes in patients with COPD; however, its prevalence and clinical implications in domestic (residential) settings remains unknown. Individuals with COPD (n=43) recruited in Singapore had their residences prospectively sampled and assessed by shotgun metagenomic...