Effect of apolipoprotein E3/4 phenotype on postprandial triglycerides and retinyl palmitate metabolism in plasma from hyperlipidemic subjects in Japan

• Published in: Atherosclerosis Vol. 154; no. 3; pp. 539 - 546
• Main Authors: Kobayashi, Junji, Saito, Yuji, Taira, Kouichi, Hikita, Minoru, Takahashi, Kazuo, Bujo, Hideaki, Morisaki, Nobuhiro, Saito, Yasushi
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier Ireland Ltd 15.02.2001
• Subjects: Adult; Aged; Apolipoprotein A-I - blood; Apolipoprotein E3; Apolipoprotein E3/4; Apolipoprotein E4; Apolipoproteins B - blood; Apolipoproteins E - blood; Apolipoproteins E - genetics; Dietary Fats - pharmacology; Female; Humans; Hyperlipidemias - blood; Hyperlipidemias - genetics; Lipids - blood; Lipoproteins - blood; Male; Middle Aged; Phenotype; Postprandial Period; Postprandial response; Retinyl palmitate; Triglycerides; Triglycerides - blood; Visceral fat; Vitamin A - analogs & derivatives; Vitamin A - blood; Vitamin A - pharmacology; Visceral fat; Apolipoprotein E3/4; Triglycerides; Postprandial response; Retinyl palmitate

In a previous study it was shown that postprandial lipid metabolism is delayed in individuals with intra-abdominal visceral fat accumulation. Population studies have shown that as compared with individuals with apolipoprotein (apo) E3/3, those with phenotype apo E3/4 phenotype have higher plasma and...