Sunitinib-Induced Hypothyroidism and Survival in Pancreatic Neuroendocrine Tumors

• Published in: Hormone and metabolic research Vol. 53; no. 12; pp. 794 - 800
• Main Authors: Mathew, Annie, Führer, Dagmar, Lahner, Harald
• Format: Journal Article
• Language: English
• Published: Rüdigerstraße 14, 70469 Stuttgart, Germany Georg Thieme Verlag 01.12.2021
• Subjects: Endocrine Care; neuroendocrinology; tyrosine kinase inhibitor; pancreatic neuroendocrine tumor; predictive factor; survival

Abstract Sunitinib has been approved for the treatment of pancreatic neuroendocrine tumors, renal-cell carcinoma, and gastrointestinal stromal tumors. The elevation of thyroid-stimulating hormone serum levels is a common side effect. Studies suggest a correlation between sunitinib-induced hypothyroi...