The Development of Tyrosyl-DNA Phosphodiesterase 1 Inhibitors. Combination of Monoterpene and Adamantine Moieties via Amide or Thioamide Bridges - Chepanova, Arina A.; Mozhaitsev, Evgenii S.; Munkuev, Aldar A.; Suslov, Evgeniy V.; Korchagina, Dina V.; Zakharova, Olga D.; Zakharenko, Alexandra L.; Patel, Jinal; Ayine-Tora, Daniel M.; Reynisson, Jóhannes; Leung, Ivanhoe K. H.; Volcho, Konstantin P.; et al. (Applied sciences, 2019)
Keywords: A-549 lung adenocarcinoma cell line l; Cancer therapies; chemical space; Chromatography; Cytotoxicity; Deoxyribonucleic acid; DNA; Enzymes; fluorescence biosensor assay; intrinsic tryptophan fluorescence binding assay; Lung cancer; molecular modelling; Solvents; synergy; thermal shift assay; Topoisomerase 1; topotecan