Active targeting of gold nanoparticles as cancer therapeutics

• Published in: Chemical Society reviews Vol. 49; no. 23; pp. 8774 - 8789
• Main Authors: Goddard, Zoë Rachael, Marín, María J., Russell, David A., Searcey, Mark
• Format: Journal Article
• Language: English
• Published: London Royal Society of Chemistry 07.12.2020
• Subjects: Antibodies; biocompatibility; Cancer; Carbohydrates; Drug carriers; Gold; Ligands; moieties; nanogold; Nanoparticles; neoplasms; oligonucleotides; Peptides; proteins; society; Toxicity

Gold nanoparticles (AuNPs) are of increasing interest for their unique properties and their biocompatability, minimal toxicity, multivalency and size tunability make them exciting drug carriers. The functionalisaton of AuNPs with targeting moieties allows for their selective delivery to cancers, wit...