Pharmacokinetics and disposition characteristics of recombinant decorin after intravenous injection into mice - Masuda, Hideo; Takakura, Yoshinobu; Hashida, Mitsuru (Biochimica et biophysica acta, 1999)
Keywords: Animals; Decorin; Extracellular Matrix Proteins; Hepatic uptake; Indium Radioisotopes; Injections, Intravenous; Liver - drug effects; Liver - metabolism; Male; Mice; Pharmacokinetics; Proteoglycan; Proteoglycans - administration & dosage; Proteoglycans - pharmacokinetics; Recombinant Proteins - pharmacokinetics; Tissue Distribution; Transforming Growth Factor beta - antagonists & inhibitors; Proteoglycan; ChS-C, chondroitin sulfate C; Decorin; BSA, bovine serum albumin; ChS-A, chondroitin sulfate A; TGF-β, transforming growth factor-β; poly[I], polyinosinic acid; Man-BSA, mannosylated BSA; Suc-BSA, succinylated BSA; Pharmacokinetics; Hepatic uptake; poly[C], polycytidylic acid