Acute chest syndrome: the role of erythro-exchange in patients with sickle cell disease in Sicily

• Published in: Transfusion and apheresis science Vol. 29; no. 1; pp. 39 - 44
• Main Authors: Lombardo, Turiddu, Rosso, Rosamaria, La Ferla, Alfio, Gabriella Ferro, Maria, Ximenes, Benedetta, Frontini, Viviana, Pennisi, Salvatore
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.08.2003
• Subjects: Acute chest syndrome; Adult; Anemia, Sickle Cell - complications; Erythro-exchange; Erythrocytes - cytology; Female; Follow-Up Studies; Haemophilus influenzae - metabolism; Health technology assessment; Hematocrit; Hemoglobin, Sickle - biosynthesis; Humans; Lung Diseases - genetics; Male; Middle Aged; Mycoplasma pneumoniae - metabolism; Sicily; Sickle cell disease; Syndrome; Time Factors; X-Rays; Sicily; Sickle cell disease; Erythro-exchange; Acute chest syndrome

Acute Chest Syndrome (ACS) describes a syndrome characterized by the presence of a new pulmonary infiltrate on a chest X-ray, fever, and respiratory symptoms and is the leading cause of death and hospitalization in sickle cell disease (SCD). We studied 21 patients affected by SCD (13 HbSβ+, 4 HbSβ°,...