Association between homocysteine and neopterin in healthy subjects measured by a simple HPLC-fluorometric method

• Published in: Clinical biochemistry Vol. 34; no. 4; pp. 271 - 275
• Main Authors: Turgan, Nevbahar, Habif, Sara, Parildar, Zuhal, Özmen, Dilek, Mutaf, Isil, Erdener, Dilek, Bayindir, Oya
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.06.2001
• Subjects: Adult; Cell-mediated immunity; Chemistry, Clinical - methods; Chromatography, High Pressure Liquid - methods; Enzyme-Linked Immunosorbent Assay - methods; Female; Fluorometry - methods; Homocysteine; Homocysteine - blood; Homocysteine - urine; Humans; Immunologic marker; Male; Middle Aged; Muscle, Smooth - cytology; Neopterin; Neopterin - blood; Neopterin - urine; Reversed-phase chromatography; Time Factors; Neopterin; Cell-mediated immunity; Homocysteine; Reversed-phase chromatography; Immunologic marker
• ISSN: 0009-9120; 1873-2933
• DOI: 10.1016/S0009-9120(01)00226-0

Objectives: Neopterin and homocysteine promote vascular smooth muscle cell proliferation through the activation of nuclear factor κ B. The aim of this study was to investigate the relation between these two compounds in healthy subjects by a rapid HPLC-fluorometric method which simplifies sample pre...