IgG subclass responses in a longitudinal study of canine visceral leishmaniasis

• Published in: Veterinary immunology and immunopathology Vol. 91; no. 3; pp. 161 - 168
• Main Authors: Quinnell, R.J., Courtenay, O., Garcez, L.M., Kaye, P.M., Shaw, M.A., Dye, C., Day, M.J.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 10.02.2003
• Subjects: Animals; Antibodies, Protozoan - classification; Antibodies, Protozoan - immunology; Dog; Dog Diseases - immunology; Dogs; Female; IgG subclass antibodies; Immunoglobulin G - blood; Immunoglobulin G - classification; Immunoglobulin G - immunology; Leishmania infantum; Leishmania infantum - immunology; Leishmaniasis, Visceral - immunology; Leishmaniasis, Visceral - veterinary; Longitudinal Studies; Male; Time Factors; Up-Regulation; Dog; Leishmania infantum; IgG subclass antibodies

Visceral leishmaniasis (VL), caused by Leishmania infantum, is an important disease of domestic dogs. Here, we present data on the IgG subclass antibody response to crude L. infantum antigen in a cohort of naturally infected Brazilian dogs. Specific IgG1–IgG4 responses could be detected in 98, 58, 7...