IgG subclass responses in a longitudinal study of canine visceral leishmaniasis
Visceral leishmaniasis (VL), caused by Leishmania infantum, is an important disease of domestic dogs. Here, we present data on the IgG subclass antibody response to crude L. infantum antigen in a cohort of naturally infected Brazilian dogs. Specific IgG1–IgG4 responses could be detected in 98, 58, 7...
Saved in:
Published in | Veterinary immunology and immunopathology Vol. 91; no. 3; pp. 161 - 168 |
---|---|
Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
Netherlands
Elsevier B.V
10.02.2003
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Visceral leishmaniasis (VL), caused by
Leishmania infantum, is an important disease of domestic dogs. Here, we present data on the IgG subclass antibody response to crude
L. infantum antigen in a cohort of naturally infected Brazilian dogs. Specific IgG1–IgG4 responses could be detected in 98, 58, 70 and 82%, respectively of 57 dogs that were seropositive for specific IgG. Levels of all IgG subclasses were strongly inter-correlated. Levels of all IgG subclasses increased at the time of seroconversion, before reaching a plateau after several months. Levels of all IgG subclasses were higher in sick dogs than healthy dogs, and levels of all except IgG2 were higher in parasite-positive (by PCR) than parasite-negative dogs. However, levels of IgG2 relative to IgG1 were lower in sick or parasite-positive dogs compared to healthy or parasite-negative infected dogs. In contrast to previous studies, the results suggest that canine VL is associated with upregulation of specific antibody of all IgG subclasses, particularly IgG1, IgG3 and IgG4. |
---|---|
AbstractList | Visceral leishmaniasis (VL), caused by
Leishmania infantum, is an important disease of domestic dogs. Here, we present data on the IgG subclass antibody response to crude
L. infantum antigen in a cohort of naturally infected Brazilian dogs. Specific IgG1–IgG4 responses could be detected in 98, 58, 70 and 82%, respectively of 57 dogs that were seropositive for specific IgG. Levels of all IgG subclasses were strongly inter-correlated. Levels of all IgG subclasses increased at the time of seroconversion, before reaching a plateau after several months. Levels of all IgG subclasses were higher in sick dogs than healthy dogs, and levels of all except IgG2 were higher in parasite-positive (by PCR) than parasite-negative dogs. However, levels of IgG2 relative to IgG1 were lower in sick or parasite-positive dogs compared to healthy or parasite-negative infected dogs. In contrast to previous studies, the results suggest that canine VL is associated with upregulation of specific antibody of all IgG subclasses, particularly IgG1, IgG3 and IgG4. Visceral leishmaniasis (VL), caused by Leishmania infantum, is an important disease of domestic dogs. Here, we present data on the IgG subclass antibody response to crude L. infantum antigen in a cohort of naturally infected Brazilian dogs. Specific IgG1-IgG4 responses could be detected in 98, 58, 70 and 82%, respectively of 57 dogs that were seropositive for specific IgG. Levels of all IgG subclasses were strongly inter-correlated. Levels of all IgG subclasses increased at the time of seroconversion, before reaching a plateau after several months. Levels of all IgG subclasses were higher in sick dogs than healthy dogs, and levels of all except IgG2 were higher in parasite-positive (by PCR) than parasite-negative dogs. However, levels of IgG2 relative to IgG1 were lower in sick or parasite-positive dogs compared to healthy or parasite-negative infected dogs. In contrast to previous studies, the results suggest that canine VL is associated with upregulation of specific antibody of all IgG subclasses, particularly IgG1, IgG3 and IgG4. |
Author | Garcez, L.M. Kaye, P.M. Quinnell, R.J. Day, M.J. Courtenay, O. Dye, C. Shaw, M.A. |
Author_xml | – sequence: 1 givenname: R.J. surname: Quinnell fullname: Quinnell, R.J. email: r.j.quinnell@leeds.ac.uk organization: School of Biology, University of Leeds, Leeds LS2 9JT, UK – sequence: 2 givenname: O. surname: Courtenay fullname: Courtenay, O. organization: Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK – sequence: 3 givenname: L.M. surname: Garcez fullname: Garcez, L.M. organization: Instituto Evandro Chagas, Belém, Pará, Brazil – sequence: 4 givenname: P.M. surname: Kaye fullname: Kaye, P.M. organization: Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK – sequence: 5 givenname: M.A. surname: Shaw fullname: Shaw, M.A. organization: School of Biology, University of Leeds, Leeds LS2 9JT, UK – sequence: 6 givenname: C. surname: Dye fullname: Dye, C. organization: Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK – sequence: 7 givenname: M.J. surname: Day fullname: Day, M.J. organization: Department of Pathology and Microbiology, University of Bristol, Langford BS40 5DU, UK |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/12586479$$D View this record in MEDLINE/PubMed |
BookMark | eNqFkE1PGzEQQK0K1IS0P6HIp6ocFvy9u6cKoTaNFCkH2rNle2ep0cYbPFkk_n0dEsGxl_HI88YzfhfkLI0JCPnC2TVn3Nzcl6AroUT9jYkrxiTnlfhA5rypZSW0VGdk_obMyAXiI2NMt03zkcy40I1RdTsnm9XDkuLkw-AQaQbcjQkBaUzU0WFMD3E_dTG5gWJJXujY0-BSTECfIwbIpTBAxL_bcukw4idy3rsB4fPpXJA_P3_8vvtVrTfL1d3tugrS8H2lWa06Xvu-gV6q3vhWeeASBKjei9aVqml4Wd35YEIfWtXJxjPTCW-48UouyNfju7s8Pk2Ae7s97DMMLsE4oa0l41pLXUB9BEMeETP0dpfj1uUXy5k9mLSvJu1Bk2XCvpq0ovRdngZMfgvde9dJXQG-HwEo33yOkC2GCClAFzOEve3G-J8R_wDHSYVM |
CitedBy_id | crossref_primary_10_1016_j_vetimm_2015_11_008 crossref_primary_10_1371_journal_pntd_0009552 crossref_primary_10_1016_j_vetpar_2004_10_008 crossref_primary_10_1017_S003118201600055X crossref_primary_10_1016_j_vetpar_2018_07_011 crossref_primary_10_1016_j_vetpar_2010_01_023 crossref_primary_10_3390_vaccines10060947 crossref_primary_10_1016_j_rvsc_2011_12_009 crossref_primary_10_1016_j_vaccine_2006_10_036 crossref_primary_10_1016_j_vetpar_2019_05_006 crossref_primary_10_1016_j_vetimm_2007_01_014 crossref_primary_10_1016_j_vetpar_2008_07_028 crossref_primary_10_1016_j_vetimm_2007_01_015 crossref_primary_10_1128_CVI_00456_09 crossref_primary_10_1016_j_vetimm_2008_10_307 crossref_primary_10_1016_j_tvjl_2006_11_006 crossref_primary_10_1051_vetres_2007015 crossref_primary_10_1016_j_vetimm_2007_05_006 crossref_primary_10_1186_s13071_021_04895_z crossref_primary_10_1016_j_vetpar_2007_06_034 crossref_primary_10_1590_S1984_29612015071 crossref_primary_10_1590_S1984_29612015073 crossref_primary_10_1016_j_vetimm_2004_08_011 crossref_primary_10_1590_S0036_46652013000200007 crossref_primary_10_1084_jem_20041470 crossref_primary_10_1016_j_vetpar_2004_10_010 crossref_primary_10_1055_a_2289_1927 crossref_primary_10_3389_fcimb_2018_00302 crossref_primary_10_1016_j_exppara_2008_08_001 crossref_primary_10_1016_j_vetpar_2008_09_001 crossref_primary_10_1111_j_1365_3164_2009_00823_x crossref_primary_10_1016_j_vetpar_2011_11_016 crossref_primary_10_1016_j_vetimm_2005_03_011 crossref_primary_10_1128_JCM_02402_09 crossref_primary_10_3389_fimmu_2018_01690 crossref_primary_10_1016_j_vetpar_2009_02_018 crossref_primary_10_1016_j_vetpar_2019_08_007 crossref_primary_10_1016_j_vetimm_2008_02_004 crossref_primary_10_1186_2052_6687_1_5 crossref_primary_10_1055_a_1970_9590 crossref_primary_10_1016_j_vetimm_2006_02_001 crossref_primary_10_1016_j_vetpar_2010_06_021 crossref_primary_10_1016_j_vetpar_2007_03_037 crossref_primary_10_1590_s1984_296120180021 crossref_primary_10_1016_j_vetimm_2006_10_004 crossref_primary_10_1111_j_1365_3024_2006_00840_x crossref_primary_10_1016_j_vaccine_2013_12_046 crossref_primary_10_1016_j_vetimm_2008_03_003 crossref_primary_10_1590_S0034_8910_2014048005224 crossref_primary_10_1016_j_vetimm_2017_06_001 crossref_primary_10_1016_j_vetimm_2009_07_017 crossref_primary_10_1016_j_actatropica_2021_105906 crossref_primary_10_1007_s11259_006_0010_3 crossref_primary_10_3390_vetsci8120293 crossref_primary_10_1007_s00436_011_2812_7 crossref_primary_10_1111_j_1939_1676_2006_tb02887_x crossref_primary_10_1590_S0036_46652014000300008 crossref_primary_10_3390_ijerph17228488 crossref_primary_10_1016_j_vaccine_2008_01_023 crossref_primary_10_1155_2009_680790 crossref_primary_10_1016_j_vaccine_2007_11_021 crossref_primary_10_1016_j_vetimm_2006_01_021 crossref_primary_10_1016_j_vetimm_2007_01_002 crossref_primary_10_1051_parasite_2017039 crossref_primary_10_1111_pim_12223 crossref_primary_10_1155_2009_802712 crossref_primary_10_1053_j_tcam_2009_06_006 crossref_primary_10_1590_S0036_46652011000500008 crossref_primary_10_1371_journal_pone_0185981 crossref_primary_10_1016_j_cvsm_2009_06_008 crossref_primary_10_1016_j_pt_2008_04_001 crossref_primary_10_1016_j_vetpar_2011_04_004 |
Cites_doi | 10.1128/IAI.62.1.229-235.1994 10.1086/319869 10.1016/S0165-2427(98)00213-X 10.1016/0022-1759(93)90295-I 10.1016/S0165-2427(97)00072-X 10.1111/j.1365-3024.1995.tb00914.x 10.1017/S0031182000078306 10.1111/j.1365-2249.1995.tb03603.x 10.1017/S0031182097001200 10.1017/S0031182001007363 10.1016/S0304-4017(00)00446-5 10.1111/j.1939-1676.1999.tb02190.x 10.1111/j.1365-2249.1994.tb06526.x 10.1128/CDLI.2.3.291-296.1995 10.1016/S0304-4017(00)00223-5 10.1128/IAI.67.12.6663-6669.1999 10.1017/S0031182099004710 10.1016/0034-5288(94)90048-5 10.1016/S0034-5288(96)90087-9 10.1016/S0165-2427(01)00270-7 10.1002/(SICI)1098-2825(2000)14:1<5::AID-JCLA2>3.0.CO;2-F 10.1046/j.1365-2249.1998.00752.x 10.1016/0165-2478(96)02529-1 10.1002/eji.1830250619 10.1016/S0034-5288(96)90088-0 10.1046/j.1365-3024.2000.00269.x 10.1086/320994 |
ContentType | Journal Article |
Copyright | 2002 Elsevier Science B.V. Copyright 2002 Elsevier Science B.V. |
Copyright_xml | – notice: 2002 Elsevier Science B.V. – notice: Copyright 2002 Elsevier Science B.V. |
DBID | CGR CUY CVF ECM EIF NPM AAYXX CITATION 7X8 |
DOI | 10.1016/S0165-2427(02)00311-2 |
DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef MEDLINE - Academic |
DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef MEDLINE - Academic |
DatabaseTitleList | MEDLINE |
Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine Veterinary Medicine |
EISSN | 1873-2534 |
EndPage | 168 |
ExternalDocumentID | 10_1016_S0165_2427_02_00311_2 12586479 S0165242702003112 |
Genre | Research Support, Non-U.S. Gov't Journal Article |
GroupedDBID | --- --K --M .GJ .~1 0R~ 123 1B1 1RT 1~. 1~5 29Q 4.4 457 4G. 53G 5VS 7-5 71M 8P~ 9JM AAAJQ AABNK AABVA AACTN AAEDT AAEDW AAIAV AAIKJ AAKOC AALCJ AALRI AAOAW AAQFI AAQXK AARKO AATLK AAXUO ABBQC ABFNM ABFRF ABGRD ABJNI ABKYH ABLVK ABMAC ABMZM ABRWV ABXDB ABYKQ ACDAQ ACGFO ACGFS ACIUM ACRLP ADBBV ADEZE ADMUD ADQTV AEBSH AEFWE AEKER AENEX AEQOU AESVU AEXOQ AFKWA AFTJW AFXIZ AGEKW AGHFR AGUBO AGYEJ AHHHB AIEXJ AIKHN AITUG AJBFU AJOXV AJRQY ALMA_UNASSIGNED_HOLDINGS AMFUW AMRAJ ANZVX ASPBG AVWKF AXJTR AZFZN BKOJK BLXMC BNPGV CBWCG CJTIS CNWQP CS3 DU5 EBS EFJIC EFLBG EJD EO8 EO9 EP2 EP3 F5P FDB FEDTE FGOYB FIRID FNPLU FYGXN G-2 G-Q GBLVA HLV HMG HVGLF HX~ HZ~ IHE J1W K-O KOM LCYCR LUGTX LW9 M41 MO0 N9A O-L O9- OAUVE OZT P-8 P-9 P2P PC. Q38 QYZTP R2- RIG ROL RPZ SAB SDF SDG SDP SES SEW SIN SNL SPCBC SSA SSH SSI SSZ SVS T5K UNMZH WUQ ~G- ~KM AAHBH AAXKI AKRWK CGR CUY CVF ECM EIF NPM AAYXX ACRPL ADNMO ADVLN AFJKZ CITATION 7X8 |
ID | FETCH-LOGICAL-c361t-5074d17bf8ef34f6b94be13e2e4fb29a74d681242abc6cfc94d38b06d2b616b43 |
IEDL.DBID | AIKHN |
ISSN | 0165-2427 |
IngestDate | Wed Dec 04 15:34:59 EST 2024 Fri Dec 06 01:09:50 EST 2024 Sat Sep 28 08:36:40 EDT 2024 Fri Feb 23 02:20:39 EST 2024 |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 3 |
Keywords | Dog Leishmania infantum IgG subclass antibodies |
Language | English |
License | Copyright 2002 Elsevier Science B.V. https://www.elsevier.com/tdm/userlicense/1.0 |
LinkModel | DirectLink |
MergedId | FETCHMERGED-LOGICAL-c361t-5074d17bf8ef34f6b94be13e2e4fb29a74d681242abc6cfc94d38b06d2b616b43 |
Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
PMID | 12586479 |
PQID | 73015535 |
PQPubID | 23479 |
PageCount | 8 |
ParticipantIDs | proquest_miscellaneous_73015535 crossref_primary_10_1016_S0165_2427_02_00311_2 pubmed_primary_12586479 elsevier_sciencedirect_doi_10_1016_S0165_2427_02_00311_2 |
PublicationCentury | 2000 |
PublicationDate | 2003-02-10 |
PublicationDateYYYYMMDD | 2003-02-10 |
PublicationDate_xml | – month: 02 year: 2003 text: 2003-02-10 day: 10 |
PublicationDecade | 2000 |
PublicationPlace | Netherlands |
PublicationPlace_xml | – name: Netherlands |
PublicationTitle | Veterinary immunology and immunopathology |
PublicationTitleAlternate | Vet Immunol Immunopathol |
PublicationYear | 2003 |
Publisher | Elsevier B.V |
Publisher_xml | – name: Elsevier B.V |
References | Quinnell, Courtenay, Davidson, Garcez, Lambson, Ramos, Shaw, Shaw, Dye (BIB24) 2001; 122 Leandro, Santos-Gomes, Campino, Romao, Cortes, Rolao, Gomes-Pereira, Rica Capela, Abranches (BIB15) 2001; 79 Anam, Afrin, Banerjee, Pramanik, Guha, Goswami, Saha, Ali (BIB1) 1999; 67 Quinnell, Courtenay, Garcez, Dye (BIB23) 1997; 115 Quinnell, Courtenay, Shaw, Day, Garcez, Dye, Kaye (BIB25) 2001; 183 Courtenay, Macdonald, Lainson, Shaw, Dye (BIB6) 1994; 109 Pinelli, Killick-Kendrick, Wagenaar, Bernadina, del Real, Ruitenberg (BIB21) 1994; 62 Ghosh, Dasgupta, Ghose (BIB13) 1995; 2 Mauricio, Howard, Stothard, Miles (BIB16) 1999; 119 Elassad, Younis, Siddig, Grayson, Petersen, Ghalib (BIB12) 1994; 95 Pinelli, Gonzalo, Boog, Rutten, Gebhard, del Real, Ruitenberg (BIB22) 1995; 25 Day, Corato, Shaw (BIB9) 1996; 61 Day (BIB8) 1996; 61 Deplazes, Smith, Arnold, Lutz, Eckert (BIB10) 1995; 17 StataCorp., 1999. Stata Statistical Software: Release 6.0. Stata Corporation, College Station, TX. Mazza, Duffus, Elson, Stokes, Wilson, Whiting (BIB17) 1993; 161 Nieto, Garcia-Alonso, Requena, Miron, Soto, Alonso, Navarrete (BIB20) 1999; 67 Mazza, Whiting, Day, Duffus (BIB18) 1994; 57 Chatterjee, Basu, Basu, Bannerjee, Pramanik, Guha, Goswami, Saha, Mandal (BIB5) 1998; 114 Bourdoiseau, Bonnefont, Hoareau, Boehringer, Stolle, Chabanne (BIB3) 1997; 59 Cavaliero, Arnold, Mathis, Glaus, Hofmann-Lehmann, Deplazes (BIB4) 1999; 13 El Amin, Wright, Vlug (BIB11) 1986; 64 Morales, Carrillo, Requena, Guzman, Gomez, Patarroyo, Alonso (BIB19) 1997; 114 Solano-Gallego, Llull, Ramos, Riera, Arboix, Alberola, Ferrer (BIB27) 2000; 90 da Matta, Hoshino-Shimizu, Dietze, Corbett (BIB7) 2000; 14 Ulrich, Rodriguez, Centeno, Convit (BIB30) 1995; 100 Boceta, Alonso, Jimenez-Ruiz (BIB2) 2000; 22 Hailu, Menon, Berhe, Gedamu, Hassard, Kager, Olobo, Bretscher (BIB14) 2001; 184 Shiddo, Huldt, Nilsson, Ouchterlony, Thorstensson (BIB26) 1996; 50 Solano-Gallego, Riera, Roura, Iniesta, Gallego, Valladares, Fisa, Castillejo, Alberola, Ferrer, Arboix, Portus (BIB28) 2001; 96 Deplazes (10.1016/S0165-2427(02)00311-2_BIB10) 1995; 17 Mazza (10.1016/S0165-2427(02)00311-2_BIB18) 1994; 57 Morales (10.1016/S0165-2427(02)00311-2_BIB19) 1997; 114 Shiddo (10.1016/S0165-2427(02)00311-2_BIB26) 1996; 50 Courtenay (10.1016/S0165-2427(02)00311-2_BIB6) 1994; 109 Ulrich (10.1016/S0165-2427(02)00311-2_BIB30) 1995; 100 Nieto (10.1016/S0165-2427(02)00311-2_BIB20) 1999; 67 Solano-Gallego (10.1016/S0165-2427(02)00311-2_BIB27) 2000; 90 Day (10.1016/S0165-2427(02)00311-2_BIB9) 1996; 61 El Amin (10.1016/S0165-2427(02)00311-2_BIB11) 1986; 64 Pinelli (10.1016/S0165-2427(02)00311-2_BIB21) 1994; 62 10.1016/S0165-2427(02)00311-2_BIB29 Quinnell (10.1016/S0165-2427(02)00311-2_BIB23) 1997; 115 Bourdoiseau (10.1016/S0165-2427(02)00311-2_BIB3) 1997; 59 da Matta (10.1016/S0165-2427(02)00311-2_BIB7) 2000; 14 Mazza (10.1016/S0165-2427(02)00311-2_BIB17) 1993; 161 Hailu (10.1016/S0165-2427(02)00311-2_BIB14) 2001; 184 Pinelli (10.1016/S0165-2427(02)00311-2_BIB22) 1995; 25 Solano-Gallego (10.1016/S0165-2427(02)00311-2_BIB28) 2001; 96 Day (10.1016/S0165-2427(02)00311-2_BIB8) 1996; 61 Cavaliero (10.1016/S0165-2427(02)00311-2_BIB4) 1999; 13 Elassad (10.1016/S0165-2427(02)00311-2_BIB12) 1994; 95 Ghosh (10.1016/S0165-2427(02)00311-2_BIB13) 1995; 2 Leandro (10.1016/S0165-2427(02)00311-2_BIB15) 2001; 79 Quinnell (10.1016/S0165-2427(02)00311-2_BIB24) 2001; 122 Anam (10.1016/S0165-2427(02)00311-2_BIB1) 1999; 67 Chatterjee (10.1016/S0165-2427(02)00311-2_BIB5) 1998; 114 Mauricio (10.1016/S0165-2427(02)00311-2_BIB16) 1999; 119 Boceta (10.1016/S0165-2427(02)00311-2_BIB2) 2000; 22 Quinnell (10.1016/S0165-2427(02)00311-2_BIB25) 2001; 183 |
References_xml | – volume: 184 start-page: 112 year: 2001 end-page: 115 ident: BIB14 article-title: Distinct immunity in patients with visceral leishmaniasis from that in subclinically infected and drug-cured people: implications for the mechanism underlying drug cure publication-title: J. Infect. Dis. contributor: fullname: Bretscher – volume: 90 start-page: 37 year: 2000 end-page: 45 ident: BIB27 article-title: The Ibizian hound presents a predominantly cellular immune response against natural publication-title: Vet. Parasitol. contributor: fullname: Ferrer – volume: 17 start-page: 451 year: 1995 end-page: 458 ident: BIB10 article-title: Specific IgG1 and IgG2 antibody responses of dogs to publication-title: Parasite Immunol. contributor: fullname: Eckert – volume: 114 start-page: 408 year: 1998 end-page: 413 ident: BIB5 article-title: Distribution of IgG subclasses in antimonial unresponsive Indian kala-azar patients publication-title: Clin. Exp. Immunol. contributor: fullname: Mandal – volume: 122 start-page: 253 year: 2001 end-page: 261 ident: BIB24 article-title: Detection of publication-title: Parasitology contributor: fullname: Dye – volume: 50 start-page: 87 year: 1996 end-page: 93 ident: BIB26 article-title: Visceral leishmaniasis in Somalia. Significance of IgG subclasses and of IgE response publication-title: Immunol. Lett. contributor: fullname: Thorstensson – volume: 95 start-page: 294 year: 1994 end-page: 299 ident: BIB12 article-title: The significance of blood levels of IgM, IgA, IgG and IgG subclasses in Sudanese visceral leishmaniasis patients publication-title: Clin. Exp. Immunol. contributor: fullname: Ghalib – volume: 25 start-page: 1594 year: 1995 end-page: 1600 ident: BIB22 article-title: publication-title: Eur. J. Immunol. contributor: fullname: Ruitenberg – volume: 22 start-page: 55 year: 2000 end-page: 62 ident: BIB2 article-title: Leucine rich repeats are the main epitopes in publication-title: Parasite Immunol. contributor: fullname: Jimenez-Ruiz – volume: 109 start-page: 273 year: 1994 end-page: 279 ident: BIB6 article-title: Epidemiology of canine leishmaniasis: a comparative serological study of dogs and foxes in Amazon Brazil publication-title: Parasitology contributor: fullname: Dye – volume: 115 start-page: 143 year: 1997 end-page: 156 ident: BIB23 article-title: The epidemiology of canine leishmaniasis: transmission rates estimated from a cohort study in Amazonian Brazil publication-title: Parasitology contributor: fullname: Dye – volume: 61 start-page: 136 year: 1996 end-page: 142 ident: BIB9 article-title: Subclass profile of allergen-specific IgG antibodies in atopic dogs publication-title: Res. Vet. Sci. contributor: fullname: Shaw – volume: 96 start-page: 265 year: 2001 end-page: 276 ident: BIB28 article-title: publication-title: Vet. Parasitol. contributor: fullname: Portus – volume: 161 start-page: 193 year: 1993 end-page: 203 ident: BIB17 article-title: The separation and identification by monoclonal antibodies of dog IgG fractions publication-title: J. Immunol. Methods contributor: fullname: Whiting – volume: 114 start-page: 507 year: 1997 end-page: 516 ident: BIB19 article-title: Mapping of the antigenic determinants of the publication-title: Parasitology contributor: fullname: Alonso – volume: 13 start-page: 330 year: 1999 end-page: 334 ident: BIB4 article-title: Clinical, serologic, and parasitologic follow-up after long-term allopurinol therapy of dogs naturally infected with publication-title: J. Vet. Internal Med. contributor: fullname: Deplazes – volume: 67 start-page: 6663 year: 1999 end-page: 6669 ident: BIB1 article-title: Differential decline in publication-title: Infect. Immun. contributor: fullname: Ali – volume: 61 start-page: 129 year: 1996 end-page: 135 ident: BIB8 article-title: IgG subclasses of canine anti-erythrocyte, anti-nuclear and anti-thyroglobulin autoantibodies publication-title: Res. Vet. Sci. contributor: fullname: Day – volume: 59 start-page: 21 year: 1997 end-page: 30 ident: BIB3 article-title: Specific IgG1 and IgG2 antibody and lymphocyte subset levels in naturally publication-title: Vet. Immunol. Immunopathol. contributor: fullname: Chabanne – volume: 62 start-page: 229 year: 1994 end-page: 235 ident: BIB21 article-title: Cellular and humoral responses in dogs experimentally and naturally infected with publication-title: Infect. Immun. contributor: fullname: Ruitenberg – volume: 57 start-page: 133 year: 1994 end-page: 139 ident: BIB18 article-title: Development of an enzyme-linked immunosorbent assay for detection of IgG subclasses in the serum of normal and diseased dogs publication-title: Res. Vet. Sci. contributor: fullname: Duffus – volume: 67 start-page: 117 year: 1999 end-page: 130 ident: BIB20 article-title: Analysis of the humoral immune response against total and recombinant antigens of publication-title: Vet. Immunol. Immunopathol. contributor: fullname: Navarrete – volume: 183 start-page: 1421 year: 2001 end-page: 1424 ident: BIB25 article-title: Tissue cytokine responses in canine visceral leishmaniasis publication-title: J. Infect. Dis. contributor: fullname: Kaye – volume: 79 start-page: 273 year: 2001 end-page: 284 ident: BIB15 article-title: Cell mediated immunity and specific IgG1 and IgG2 antibody response in natural and experimental canine leishmaniosis publication-title: Vet. Immunol. Immunopathol. contributor: fullname: Abranches – volume: 64 start-page: 14 year: 1986 end-page: 19 ident: BIB11 article-title: Characterization of the humoral immune response in Sudanese leishmaniasis: specific antibody detected by class and subclass-specific reagents publication-title: Clin. Exp. Immunol. contributor: fullname: Vlug – volume: 119 start-page: 237 year: 1999 end-page: 246 ident: BIB16 article-title: Genomic diversity in the publication-title: Parasitology contributor: fullname: Miles – volume: 14 start-page: 5 year: 2000 end-page: 12 ident: BIB7 article-title: Detection of specific antibody isotypes and subtypes before and after treatment of American visceral leishmaniasis publication-title: J. Clin. Lab. Anal. contributor: fullname: Corbett – volume: 2 start-page: 291 year: 1995 end-page: 296 ident: BIB13 article-title: Immunoglobulin G subclass-specific antileishmanial antibody responses in Indian kala-azar and post-kala-azar dermal leishmaniasis publication-title: Clin. Diagn. Lab. Immunol. contributor: fullname: Ghose – volume: 100 start-page: 54 year: 1995 end-page: 58 ident: BIB30 article-title: Differing antibody IgG isotypes in the polar forms of leprosy and cutaneous leishmaniasis characterized by antigen-specific T-cell energy publication-title: Clin. Exp. Immunol. contributor: fullname: Convit – volume: 64 start-page: 14 year: 1986 ident: 10.1016/S0165-2427(02)00311-2_BIB11 article-title: Characterization of the humoral immune response in Sudanese leishmaniasis: specific antibody detected by class and subclass-specific reagents publication-title: Clin. Exp. Immunol. contributor: fullname: El Amin – volume: 62 start-page: 229 year: 1994 ident: 10.1016/S0165-2427(02)00311-2_BIB21 article-title: Cellular and humoral responses in dogs experimentally and naturally infected with Leishmania infantum publication-title: Infect. Immun. doi: 10.1128/IAI.62.1.229-235.1994 contributor: fullname: Pinelli – volume: 183 start-page: 1421 year: 2001 ident: 10.1016/S0165-2427(02)00311-2_BIB25 article-title: Tissue cytokine responses in canine visceral leishmaniasis publication-title: J. Infect. Dis. doi: 10.1086/319869 contributor: fullname: Quinnell – volume: 67 start-page: 117 year: 1999 ident: 10.1016/S0165-2427(02)00311-2_BIB20 article-title: Analysis of the humoral immune response against total and recombinant antigens of Leishmania infantum: correlation with disease progression in canine experimental leishmaniasis publication-title: Vet. Immunol. Immunopathol. doi: 10.1016/S0165-2427(98)00213-X contributor: fullname: Nieto – volume: 161 start-page: 193 year: 1993 ident: 10.1016/S0165-2427(02)00311-2_BIB17 article-title: The separation and identification by monoclonal antibodies of dog IgG fractions publication-title: J. Immunol. Methods doi: 10.1016/0022-1759(93)90295-I contributor: fullname: Mazza – volume: 59 start-page: 21 year: 1997 ident: 10.1016/S0165-2427(02)00311-2_BIB3 article-title: Specific IgG1 and IgG2 antibody and lymphocyte subset levels in naturally Leishmania infantum-infected treated and untreated dogs publication-title: Vet. Immunol. Immunopathol. doi: 10.1016/S0165-2427(97)00072-X contributor: fullname: Bourdoiseau – volume: 17 start-page: 451 year: 1995 ident: 10.1016/S0165-2427(02)00311-2_BIB10 article-title: Specific IgG1 and IgG2 antibody responses of dogs to Leishmania infantum and other parasites publication-title: Parasite Immunol. doi: 10.1111/j.1365-3024.1995.tb00914.x contributor: fullname: Deplazes – volume: 109 start-page: 273 year: 1994 ident: 10.1016/S0165-2427(02)00311-2_BIB6 article-title: Epidemiology of canine leishmaniasis: a comparative serological study of dogs and foxes in Amazon Brazil publication-title: Parasitology doi: 10.1017/S0031182000078306 contributor: fullname: Courtenay – volume: 100 start-page: 54 year: 1995 ident: 10.1016/S0165-2427(02)00311-2_BIB30 article-title: Differing antibody IgG isotypes in the polar forms of leprosy and cutaneous leishmaniasis characterized by antigen-specific T-cell energy publication-title: Clin. Exp. Immunol. doi: 10.1111/j.1365-2249.1995.tb03603.x contributor: fullname: Ulrich – volume: 115 start-page: 143 year: 1997 ident: 10.1016/S0165-2427(02)00311-2_BIB23 article-title: The epidemiology of canine leishmaniasis: transmission rates estimated from a cohort study in Amazonian Brazil publication-title: Parasitology doi: 10.1017/S0031182097001200 contributor: fullname: Quinnell – volume: 122 start-page: 253 year: 2001 ident: 10.1016/S0165-2427(02)00311-2_BIB24 article-title: Detection of Leishmania infantum by PCR, serology and cellular immune response in a cohort study of Brazilian dogs publication-title: Parasitology doi: 10.1017/S0031182001007363 contributor: fullname: Quinnell – volume: 96 start-page: 265 year: 2001 ident: 10.1016/S0165-2427(02)00311-2_BIB28 article-title: Leishmania infantum-specific IgG, IgG1 and IgG2 antibody responses in healthy and ill dogs from endemic areas. Evolution in the course of infection and after treatment publication-title: Vet. Parasitol. doi: 10.1016/S0304-4017(00)00446-5 contributor: fullname: Solano-Gallego – volume: 13 start-page: 330 year: 1999 ident: 10.1016/S0165-2427(02)00311-2_BIB4 article-title: Clinical, serologic, and parasitologic follow-up after long-term allopurinol therapy of dogs naturally infected with Leishmania infantum publication-title: J. Vet. Internal Med. doi: 10.1111/j.1939-1676.1999.tb02190.x contributor: fullname: Cavaliero – volume: 95 start-page: 294 year: 1994 ident: 10.1016/S0165-2427(02)00311-2_BIB12 article-title: The significance of blood levels of IgM, IgA, IgG and IgG subclasses in Sudanese visceral leishmaniasis patients publication-title: Clin. Exp. Immunol. doi: 10.1111/j.1365-2249.1994.tb06526.x contributor: fullname: Elassad – volume: 2 start-page: 291 year: 1995 ident: 10.1016/S0165-2427(02)00311-2_BIB13 article-title: Immunoglobulin G subclass-specific antileishmanial antibody responses in Indian kala-azar and post-kala-azar dermal leishmaniasis publication-title: Clin. Diagn. Lab. Immunol. doi: 10.1128/CDLI.2.3.291-296.1995 contributor: fullname: Ghosh – volume: 90 start-page: 37 year: 2000 ident: 10.1016/S0165-2427(02)00311-2_BIB27 article-title: The Ibizian hound presents a predominantly cellular immune response against natural Leishmania infection publication-title: Vet. Parasitol. doi: 10.1016/S0304-4017(00)00223-5 contributor: fullname: Solano-Gallego – volume: 67 start-page: 6663 year: 1999 ident: 10.1016/S0165-2427(02)00311-2_BIB1 article-title: Differential decline in Leishmania membrane antigen-specific immunoglobulin G (IgG), IgM, IgE and IgG subclass antibodies in Indian kala-azar patients after chemotherapy publication-title: Infect. Immun. doi: 10.1128/IAI.67.12.6663-6669.1999 contributor: fullname: Anam – volume: 119 start-page: 237 year: 1999 ident: 10.1016/S0165-2427(02)00311-2_BIB16 article-title: Genomic diversity in the Leishmania donovani complex publication-title: Parasitology doi: 10.1017/S0031182099004710 contributor: fullname: Mauricio – volume: 57 start-page: 133 year: 1994 ident: 10.1016/S0165-2427(02)00311-2_BIB18 article-title: Development of an enzyme-linked immunosorbent assay for detection of IgG subclasses in the serum of normal and diseased dogs publication-title: Res. Vet. Sci. doi: 10.1016/0034-5288(94)90048-5 contributor: fullname: Mazza – volume: 61 start-page: 129 year: 1996 ident: 10.1016/S0165-2427(02)00311-2_BIB8 article-title: IgG subclasses of canine anti-erythrocyte, anti-nuclear and anti-thyroglobulin autoantibodies publication-title: Res. Vet. Sci. doi: 10.1016/S0034-5288(96)90087-9 contributor: fullname: Day – volume: 114 start-page: 507 year: 1997 ident: 10.1016/S0165-2427(02)00311-2_BIB19 article-title: Mapping of the antigenic determinants of the Leishmania infantum gp63 protein recognized by antibodies elicited during canine visceral leishmaniasis publication-title: Parasitology contributor: fullname: Morales – volume: 79 start-page: 273 year: 2001 ident: 10.1016/S0165-2427(02)00311-2_BIB15 article-title: Cell mediated immunity and specific IgG1 and IgG2 antibody response in natural and experimental canine leishmaniosis publication-title: Vet. Immunol. Immunopathol. doi: 10.1016/S0165-2427(01)00270-7 contributor: fullname: Leandro – volume: 14 start-page: 5 year: 2000 ident: 10.1016/S0165-2427(02)00311-2_BIB7 article-title: Detection of specific antibody isotypes and subtypes before and after treatment of American visceral leishmaniasis publication-title: J. Clin. Lab. Anal. doi: 10.1002/(SICI)1098-2825(2000)14:1<5::AID-JCLA2>3.0.CO;2-F contributor: fullname: da Matta – volume: 114 start-page: 408 year: 1998 ident: 10.1016/S0165-2427(02)00311-2_BIB5 article-title: Distribution of IgG subclasses in antimonial unresponsive Indian kala-azar patients publication-title: Clin. Exp. Immunol. doi: 10.1046/j.1365-2249.1998.00752.x contributor: fullname: Chatterjee – volume: 50 start-page: 87 year: 1996 ident: 10.1016/S0165-2427(02)00311-2_BIB26 article-title: Visceral leishmaniasis in Somalia. Significance of IgG subclasses and of IgE response publication-title: Immunol. Lett. doi: 10.1016/0165-2478(96)02529-1 contributor: fullname: Shiddo – volume: 25 start-page: 1594 year: 1995 ident: 10.1016/S0165-2427(02)00311-2_BIB22 article-title: Leishmania infantum-specific T cell lines derived from asymptomatic dogs that lyse infected macrophages in a major histocompatibility complex-restricted manner publication-title: Eur. J. Immunol. doi: 10.1002/eji.1830250619 contributor: fullname: Pinelli – volume: 61 start-page: 136 year: 1996 ident: 10.1016/S0165-2427(02)00311-2_BIB9 article-title: Subclass profile of allergen-specific IgG antibodies in atopic dogs publication-title: Res. Vet. Sci. doi: 10.1016/S0034-5288(96)90088-0 contributor: fullname: Day – ident: 10.1016/S0165-2427(02)00311-2_BIB29 – volume: 22 start-page: 55 year: 2000 ident: 10.1016/S0165-2427(02)00311-2_BIB2 article-title: Leucine rich repeats are the main epitopes in Leishmania infantum PSA during canine and human visceral leishmaniasis publication-title: Parasite Immunol. doi: 10.1046/j.1365-3024.2000.00269.x contributor: fullname: Boceta – volume: 184 start-page: 112 year: 2001 ident: 10.1016/S0165-2427(02)00311-2_BIB14 article-title: Distinct immunity in patients with visceral leishmaniasis from that in subclinically infected and drug-cured people: implications for the mechanism underlying drug cure publication-title: J. Infect. Dis. doi: 10.1086/320994 contributor: fullname: Hailu |
SSID | ssj0005988 |
Score | 2.0118353 |
Snippet | Visceral leishmaniasis (VL), caused by
Leishmania infantum, is an important disease of domestic dogs. Here, we present data on the IgG subclass antibody... Visceral leishmaniasis (VL), caused by Leishmania infantum, is an important disease of domestic dogs. Here, we present data on the IgG subclass antibody... |
SourceID | proquest crossref pubmed elsevier |
SourceType | Aggregation Database Index Database Publisher |
StartPage | 161 |
SubjectTerms | Animals Antibodies, Protozoan - classification Antibodies, Protozoan - immunology Dog Dog Diseases - immunology Dogs Female IgG subclass antibodies Immunoglobulin G - blood Immunoglobulin G - classification Immunoglobulin G - immunology Leishmania infantum Leishmania infantum - immunology Leishmaniasis, Visceral - immunology Leishmaniasis, Visceral - veterinary Longitudinal Studies Male Time Factors Up-Regulation |
Title | IgG subclass responses in a longitudinal study of canine visceral leishmaniasis |
URI | https://dx.doi.org/10.1016/S0165-2427(02)00311-2 https://www.ncbi.nlm.nih.gov/pubmed/12586479 https://search.proquest.com/docview/73015535 |
Volume | 91 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LT8MwDI4GSIgLgvF-jBw4wKFbkyZpe0QI2EAbBx7aLWraBCqNDdGNI7-dOG01OExIXNM6jezEduPPNkKnGdVcxZrbn5zEeCwjFEreBh7jPNBZTOwBhPuO_kB0n9jtkA8b6LLOhQFYZaX7S53utHU10qm42XnP884DJOJYAxP6gK8i0Gl4xZojiNWuXPTuuoM50iN27SfhfYiAhvNEnnISN3jm03M3j0cXmahFLqgzRdcbaL3yIfFFucxN1NDjJlrtV1HyJmo-A8bFJdrienQL3fdebnAxUyn4y_ijxMbqAudjnODRBPoWzTLokYVdyVk8Mdiy3ZLiz7xI4eoKj3RevELBjKTIi230dH31eNn1qnYKXhoIMvWs52dlESoTaRMwI1TMlCaBppoZRePEPoViZIwmKhWpSWOWBZHyRUaVIEKxYActjydjvYewCEPDMu1bIWeM-0QZ66ppERAVxcqKYh-1aw7K97JqhvwBJxNcAsulT11pUiItQVTzWf4Sv7Sa_S_Sk1ou8g34MQKU8GRWSFBedsvxfbRbimu-FsojwcL44P-fPURrDtcHvWH8I7Q8_ZjpY-ufTFULLbW_SKvahd-cud3C |
link.rule.ids | 314,780,784,4502,24116,27924,27925,45585,45679 |
linkProvider | Elsevier |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1NT-MwELUQSCwXBIWF7vLhAwc4ZBs7tpMcEQJaoOUArLhZcWJDpNIi0u7v3xknUeGAkLg6Gceasccv9psZQo4KbqVJrYSfnMwFomAcU95GgZAyskXKYAHiecdwpPoP4upRPi6RszYWBmmVje-vfbr31k1Lr9Fm77Use3cYiAMbTBwiv4phpeEVQAMxTO2V08F1f7RgeqS-_CS-jzeg8SKQp-7ENx6H_MT3E_DPtqjPIKjfii42yHqDIelpPcxNsmQnHbI6bG7JO6TzFzkuPtCWtq1b5HbwdEmruckRL9O3mhtrK1pOaEbHU6xbNC-wRhb1KWfp1FFQO4jSf2WV49EVHduyesaEGVlVVtvk4eL8_qwfNOUUgjxSbBYA8gNbxMYl1kXCKZMKY1lkuRXO8DSDp5iMTPDM5Cp3eSqKKDGhKrhRTBkR_STLk-nE7hKq4tiJwoZg5ELIkBkHUM2qiJkkNWCKLvnTalC_1lkz9Ds6mZIaVa5D7lOTMg0CSatn_cH8Gjz7V6KHrV30C-pjjCzh6bzS6Lxgysku2anNtRgLl4kScfrr-589JD_698MbfTMYXf8ma57jh3Viwj2yPHub233AKjNz0MzF_xTS378 |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=IgG+subclass+responses+in+a+longitudinal+study+of+canine+visceral+leishmaniasis&rft.jtitle=Veterinary+immunology+and+immunopathology&rft.au=Quinnell%2C+R.J.&rft.au=Courtenay%2C+O.&rft.au=Garcez%2C+L.M.&rft.au=Kaye%2C+P.M.&rft.date=2003-02-10&rft.pub=Elsevier+B.V&rft.issn=0165-2427&rft.eissn=1873-2534&rft.volume=91&rft.issue=3&rft.spage=161&rft.epage=168&rft_id=info:doi/10.1016%2FS0165-2427%2802%2900311-2&rft.externalDocID=S0165242702003112 |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0165-2427&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0165-2427&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0165-2427&client=summon |